2021
Diagnostic Accuracy of Serum Hyaluronan for Detecting HCV Infection and Liver Fibrosis in Asymptomatic Blood Donors
Rodart I, Pares M, Mendes A, Accardo C, Martins J, Silva C, Carvalho F, Barreto J, Reis M, Tersariol I, Nader H. Diagnostic Accuracy of Serum Hyaluronan for Detecting HCV Infection and Liver Fibrosis in Asymptomatic Blood Donors. Molecules 2021, 26: 3892. PMID: 34202190, PMCID: PMC8270308, DOI: 10.3390/molecules26133892.Peer-Reviewed Original ResearchConceptsHepatitis C virusAsymptomatic blood donorsLiver fibrosisBlood donorsSerum hyaluronanHCV infectionSerum levelsGGT serum levelsHA serum levelsHCV RNA detectionHCV viral loadProgressive liver diseaseAdvanced liver fibrosisHigher ALT levelsSignificant liver fibrosisNormal ALTHCV viremiaALT levelsAntiviral treatmentAsymptomatic personsBiopsy confirmationHCV samplesLiver biomarkersLiver diseaseViral load
2006
Prevalence of hepatitis C virus (HCV) infection and HCV genotypes of hemodialysis patients in Salvador, Northeastern Brazil
Silva L, Silva M, Rodart I, Lopes G, Costa F, Melo M, Gusmão E, Reis M. Prevalence of hepatitis C virus (HCV) infection and HCV genotypes of hemodialysis patients in Salvador, Northeastern Brazil. Brazilian Journal Of Medical And Biological Research 2006, 39: 595-602. PMID: 16648896, DOI: 10.1590/s0100-879x2006000500005.Peer-Reviewed Original ResearchConceptsHepatitis C virus infectionCandidate blood donorsC virus infectionHD patientsHCV infectionBlood donorsGenotype 1Virus infectionAnti-HCV seroprevalenceAnti-HCV prevalenceHCV genotype distributionAnti-HCV antibodiesHCV genotype 1Chronic liver diseaseTransfusion-transmitted infectionsCross-sectional studyDifferent dialysis centresHCV seroprevalenceChronic hemodialysisHemodialysis populationHCV RNAPositive patientsHemodialysis patientsHCV genotypesLiver disease
2003
Comparative study of Hepatitis C virus genotypes 1 and 3 in Salvador, Bahia
Codes L, de Freitas L, Jesus R, Vitvitski L, Silva L, Trepo C, Reis M, Paraná R. Comparative study of Hepatitis C virus genotypes 1 and 3 in Salvador, Bahia. The Brazilian Journal Of Infectious Diseases 2003, 7: 409-417. PMID: 14636481, DOI: 10.1590/s1413-86702003000600009.Peer-Reviewed Original ResearchConceptsHepatitis C virusC virusMost patientsSubtype 3aAverage agePositive anti-HCV resultsAnti-HCV resultsNecro-inflammatory activityDevelopment of cirrhosisOutpatient medical recordsSignificant differencesIllicit drug useMETAVIR classificationThyroid dysfunctionYounger patientsHistopathological findingsInflammatory activityLymphoid folliclesEpidemiological characteristicsRNA-HCVGenotype 3Medical recordsSubtype 1bAlcohol consumersGenotype 1
2000
Hepatitis C virus genotypes in a northeastern area of Brazil.
Silva L, Paraná R, Souza S, Berby F, Kay A, Trepó C, Santana N, Cotrim H, Lyra L, Reis M. Hepatitis C virus genotypes in a northeastern area of Brazil. American Journal Of Tropical Medicine And Hygiene 2000, 62: 257-60. PMID: 10813481, DOI: 10.4269/ajtmh.2000.62.257.Peer-Reviewed Original ResearchConceptsHepatitis C virusReverse transcription-polymerase chain reactionC virusGenotyping of HCVTranscription-polymerase chain reactionSeropositive serum samplesGenotype-specific primersWarrants further investigationGenotype 3Subtype 1aAlanine aminotransferaseGenotype distributionAspartate aminotransferaseSerum samplesMixed genotypesChain reactionViral RNACity of SalvadorFurther investigationAminotransferaseVirusBrazilian samplePatientsHigh frequencyGenotypes