2021
Leptospira interrogans biofilm formation in Rattus norvegicus (Norway rats) natural reservoirs
Santos A, dos Santos Ribeiro P, da França G, Souza F, Ramos E, Figueira C, Reis M, Costa F, Ristow P. Leptospira interrogans biofilm formation in Rattus norvegicus (Norway rats) natural reservoirs. PLOS Neglected Tropical Diseases 2021, 15: e0009736. PMID: 34495971, PMCID: PMC8451993, DOI: 10.1371/journal.pntd.0009736.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiofilmsDisease ReservoirsKidneyLeptospira interrogansLeptospirosisMaleRatsRodent DiseasesConceptsRenal tubulesPathogenic LeptospiraPathogenesis of leptospirosisMain reservoir hostsNatural animal reservoirsBacterial carriageChronic colonizationLeptospiral colonizationRenal carriageAnimal reservoirsLeptospira interrogansLeptospirosisUrban slumsCausative agentLeptospiraTubulesPossible roleReservoir hostsCarriageNatural reservoirBiofilm formationOcclusion patternsBacterial survivalHost reservoirsR. norvegicus
2017
A survey of zoonotic pathogens carried by house mouse and black rat populations in Yucatan, Mexico
PANTI-MAY J, DE ANDRADE R, GURUBEL-GONZÁLEZ Y, PALOMO-ARJONA E, SODÁ-TAMAYO L, MEZA-SULÚ J, RAMÍREZ-SIERRA M, DUMONTEIL E, VIDAL-MARTÍNEZ V, MACHAÍN-WILLIAMS C, DE OLIVEIRA D, REIS M, TORRES-CASTRO M, ROBLES M, HERNÁNDEZ-BETANCOURT S, COSTA F. A survey of zoonotic pathogens carried by house mouse and black rat populations in Yucatan, Mexico. Epidemiology And Infection 2017, 145: 2287-2295. PMID: 28689507, PMCID: PMC6231242, DOI: 10.1017/s0950268817001352.Peer-Reviewed Original ResearchConceptsH. diminutaZoonotic pathogensPolymerase chain reactionRatsMiceTropical diseasesCruzi DNALeptospira interrogansChain reactionL. interrogansT. cruziFurther studiesHymenolepis diminutaPublic healthReservoir hostsTrypanosoma cruziSedimentation techniqueInterrogansPathogensHouse miceCruziDiminutaImportant reservoirEpidemiologyPrevalence
2016
Factors affecting carriage and intensity of infection of Calodium hepaticum within Norway rats (Rattus norvegicus) from an urban slum environment in Salvador, Brazil
WALKER R, CARVALHO-PEREIRA T, SERRANO S, PEDRA G, HACKER K, TAYLOR J, MINTER A, PERTILE A, PANTI-MAY A, CARVALHO M, SOUZA FN, NERY N, RODRIGUES G, BAHIENSE T, REIS MG, KO AI, CHILDS JE, BEGON M, COSTA F. Factors affecting carriage and intensity of infection of Calodium hepaticum within Norway rats (Rattus norvegicus) from an urban slum environment in Salvador, Brazil. Epidemiology And Infection 2016, 145: 334-338. PMID: 27780498, PMCID: PMC6247895, DOI: 10.1017/s0950268816002259.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrazilCapillariaCarrier StateEnoplida InfectionsParasite LoadPoverty AreasPrevalenceRatsRisk FactorsRodent DiseasesConceptsIntensity of infectionNorway ratsIndependent risk factorC. hepaticumHumans of exposureUrban slum environmentsCalodium hepaticumUrban slum areaSlum areasLiver involvementMammalian hostsRisk factorsInfective eggsRatsCarriage levelsSignificant riskInfectionUrban slumsCarriageFurther studiesSub-standard living conditionsRiskZoonotic pathogensSlum environmentRodent-borne zoonotic pathogensLeptospira in breast tissue and milk of urban Norway rats (Rattus norvegicus)
DE OLIVEIRA D, FIGUEIRA CP, ZHAN L, PERTILE AC, PEDRA GG, GUSMÃO IM, WUNDER EA, RODRIGUES G, RAMOS EA, KO AI, CHILDS JE, REIS MG, COSTA F. Leptospira in breast tissue and milk of urban Norway rats (Rattus norvegicus). Epidemiology And Infection 2016, 144: 2420-2429. PMID: 27019024, PMCID: PMC5437553, DOI: 10.1017/s0950268816000637.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionBreast tissuePresence of leptospiresNorway ratsMajor public health concernMilk-borne transmissionMajor pathological changesReal-time polymerase chain reactionPublic health concernQuantitative real-time polymerase chain reactionPathogenic Leptospira sppBreast tissue samplesChronic carriagePathological changesLactating ratsRatsHealth concernImmunofluorescence assaysLeptospira sppGenus LeptospiraTissue samplesUrban slumsChain reactionLeptospiresLeptospira
2007
Morphological Alterations in the Kidney of Rats with Natural and Experimental Leptospira Infection
de Faria M, Athanazio DA, Ramos E, Silva EF, Reis MG, Ko AI. Morphological Alterations in the Kidney of Rats with Natural and Experimental Leptospira Infection. Journal Of Comparative Pathology 2007, 137: 231-238. PMID: 17996544, DOI: 10.1016/j.jcpa.2007.08.001.Peer-Reviewed Original ResearchConceptsInterstitial nephritisPathology of leptospirosisKidneys of ratsMorphological alterationsPathogenesis of leptospirosisFiocruz L1-130Leptospiral diseaseWistar ratsLeptospira infectionPathological changesUrban outbreaksRecreational exposureHuman infectionsL1-130RatsWidespread anthropozoonosisKidneyLeptospira interrogansLeptospirosisNephritisInfectionDiseaseEmergent diseaseMammalian reservoirsHost resistance