2024
Overestimation of Severe Acute Respiratory Syndrome Coronavirus 2 Household Transmission in Settings of High Community Transmission: Insights From an Informal Settlement Community in Salvador, Brazil
Ticona J, Nery N, Hitchings M, Belitardo E, Fofana M, Dorión M, Victoriano R, Cruz J, Santana J, de Moraes L, Cardoso C, Ribeiro G, Reis M, Khouri R, Costa F, Ko A, Cummings D. Overestimation of Severe Acute Respiratory Syndrome Coronavirus 2 Household Transmission in Settings of High Community Transmission: Insights From an Informal Settlement Community in Salvador, Brazil. Open Forum Infectious Diseases 2024, 11: ofae065. PMID: 38516384, PMCID: PMC10957159, DOI: 10.1093/ofid/ofae065.Peer-Reviewed Original ResearchSARS-CoV-2Household transmissionRT-PCR positive casesSecondary attack rateAttack rateSARS-CoV-2 infectionSARS-CoV-2 Omicron variantRisk of infectionCommunity acquisitionTherapeutic optionsCOVID-19-related symptomsCase-finding studyHousehold contactsAcquisition of SARS-CoV-2Increased riskSymptom onsetSecondary infectionBooster vaccinationSevere outcomesBiweekly visitsHighest attack rateRT-PCRInfectionCOVID-19 severe outcomesOmicron BA
2020
Accuracy of the Zika IgM Antibody Capture Enzyme-Linked Immunosorbent Assay from the Centers for Disease Control and Prevention (CDC Zika MAC-ELISA) for Diagnosis of Zika Virus Infection
Portilho M, de Moraes L, Kikuti M, Nascimento L, Reis M, Boaventura V, Khouri R, Ribeiro G. Accuracy of the Zika IgM Antibody Capture Enzyme-Linked Immunosorbent Assay from the Centers for Disease Control and Prevention (CDC Zika MAC-ELISA) for Diagnosis of Zika Virus Infection. Diagnostics 2020, 10: 835. PMID: 33080935, PMCID: PMC7603149, DOI: 10.3390/diagnostics10100835.Peer-Reviewed Original ResearchDays post-symptom onsetZika virus infectionConvalescent-phase seraVirus infectionRT-PCRDengue virusSerological diagnosisDengue casesPost-symptom onsetConvalescent-phase samplesBlood donor samplesIgM antibody capture enzymeEnzyme-linked immunosorbent assayZika IgM antibodySymptom onsetDENV infectionIgM antibodiesZIKV infectionBlood donorsDonor samplesCapture enzymeOutbreak investigationDisease controlInfectionImmunosorbent assayMeningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil
Ferreira V, Ferreira Í, Chang H, Nunes A, Topaz N, Pimentel E, Moura A, Ribeiro G, Feitosa C, Reis M, Wang X, Campos L. Meningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil. Vaccine 2020, 38: 2995-3002. PMID: 32115294, DOI: 10.1016/j.vaccine.2020.02.050.Peer-Reviewed Original ResearchConceptsMeningococcal carriageCarriage prevalenceRT-PCRN. meningitidisYoung adultsMeningococcal carriage studyMeningococcal serogroup CCross-sectional studyMeningococcal carriage prevalenceAppropriate vaccination strategiesStandard microbiology methodsSix yearsMeningococcal carriage isolatesNG isolatesMale sexSerogroup CHerd protectionVaccination strategiesCarriage isolatesCarriage studiesOropharyngeal swabsReal-time PCRNull genotypeContinuous vaccinationNeisseria meningitidis
2019
Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses
Kikuti M, Tauro L, Moreira P, Nascimento L, Portilho M, Soares G, Weaver S, Reis M, Kitron U, Ribeiro G. Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses. International Journal Of Infectious Diseases 2019, 91: 38-43. PMID: 31704226, DOI: 10.1016/j.ijid.2019.11.001.Peer-Reviewed Original ResearchConceptsConvalescent samplesIgM enzymeRT-PCRZika virus transmissionNegative patientsCHIKV infectionAcute samplesZIKV casesConvalescent seraSurveillance studyCHIKV transmissionZika virusCHIKV casesDiagnostic performanceLow specificityVirus transmissionEquivocal resultsTest sensitivitySerumELISA specificityPatientsHigh rateDengueConcomitant transmissionMore equivocal results