Diagnostic Accuracy of Serum Hyaluronan for Detecting HCV Infection and Liver Fibrosis in Asymptomatic Blood Donors
Rodart I, Pares M, Mendes A, Accardo C, Martins J, Silva C, Carvalho F, Barreto J, Reis M, Tersariol I, Nader H. Diagnostic Accuracy of Serum Hyaluronan for Detecting HCV Infection and Liver Fibrosis in Asymptomatic Blood Donors. Molecules 2021, 26: 3892. PMID: 34202190, PMCID: PMC8270308, DOI: 10.3390/molecules26133892.Peer-Reviewed Original ResearchConceptsHepatitis C virusAsymptomatic blood donorsLiver fibrosisBlood donorsSerum hyaluronanHCV infectionSerum levelsGGT serum levelsHA serum levelsHCV RNA detectionHCV viral loadProgressive liver diseaseAdvanced liver fibrosisHigher ALT levelsSignificant liver fibrosisNormal ALTHCV viremiaALT levelsAntiviral treatmentAsymptomatic personsBiopsy confirmationHCV samplesLiver biomarkersLiver diseaseViral load