Leptospira interrogans biofilm formation in Rattus norvegicus (Norway rats) natural reservoirs
Santos A, dos Santos Ribeiro P, da França G, Souza F, Ramos E, Figueira C, Reis M, Costa F, Ristow P. Leptospira interrogans biofilm formation in Rattus norvegicus (Norway rats) natural reservoirs. PLOS Neglected Tropical Diseases 2021, 15: e0009736. PMID: 34495971, PMCID: PMC8451993, DOI: 10.1371/journal.pntd.0009736.Peer-Reviewed Original ResearchConceptsRenal tubulesPathogenic LeptospiraPathogenesis of leptospirosisMain reservoir hostsNatural animal reservoirsBacterial carriageChronic colonizationLeptospiral colonizationRenal carriageAnimal reservoirsLeptospira interrogansLeptospirosisUrban slumsCausative agentLeptospiraTubulesPossible roleReservoir hostsCarriageNatural reservoirBiofilm formationOcclusion patternsBacterial survivalHost reservoirsR. norvegicus