Clinical and molecular characteristics of sickle cell anemia in the northeast of Brazil
Adorno E, Zanette Â, Lyra I, Seixas M, Reis M, Gonçalves M. Clinical and molecular characteristics of sickle cell anemia in the northeast of Brazil. Genetics And Molecular Biology 2008, 31: 621-625. DOI: 10.1590/s1415-47572008000400003.Peer-Reviewed Original ResearchSevere sickle cell anemiaSickle cell anemiaCell anemiaBeta S-globin gene haplotypesMean hemoglobin concentrationLow mean corpuscular volumeMean corpuscular volumeErythrocyte transfusionCerebrovascular accidentHigher mean hemoglobin concentrationHigh HbF levelsClinical dataCAR haplotypeHemoglobin concentrationCorpuscular volumeCorpuscular hemoglobinOutpatientsHbF levelsFetal hemoglobinAnemiaPCR-RFLPCarrier valuesHemoglobinGene haplotypesMolecular characteristics