2022
Impact of Chemoembolic Regimen on Immune Cell Recruitment and Immune Checkpoint Marker Expression following Transcatheter Arterial Chemoembolization in a VX2 Rabbit Liver Tumor Model
Berz AM, Santana JG, Iseke S, Gross M, Pekurovsky V, Laage Gaupp F, Savic LJ, Borde T, Gottwald LA, Boustani AM, Gebauer B, Lin M, Zhang X, Schlachter T, Madoff DC, Chapiro J. Impact of Chemoembolic Regimen on Immune Cell Recruitment and Immune Checkpoint Marker Expression following Transcatheter Arterial Chemoembolization in a VX2 Rabbit Liver Tumor Model. Journal Of Vascular And Interventional Radiology 2022, 33: 764-774.e4. PMID: 35346859, PMCID: PMC9344951, DOI: 10.1016/j.jvir.2022.03.026.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibiotics, AntineoplasticBicarbonatesCarcinoma, HepatocellularChemoembolization, TherapeuticDoxorubicinLiver NeoplasmsProgrammed Cell Death 1 ReceptorRabbitsConceptsTranscatheter arterial chemoembolizationCytotoxic T-lymphocyte-associated protein 4Rabbit liver tumor modelConventional TACEImmune checkpoint marker expressionLiver tumor modelVX2 rabbit liver tumor modelArterial chemoembolizationBicarbonate infusionImmune responseDifferentiation 3T-lymphocyte-associated protein 4Conventional transcatheter arterial chemoembolizationTumor modelCell death protein 1Marker expressionIntratumoral T cellsImmune checkpoint markersT cell infiltrationDeath protein 1Antigen-presenting cellsImmune cell recruitmentNew Zealand white rabbitsZealand white rabbitsAPC infiltration
2015
Multimodality 3D Tumor Segmentation in HCC Patients Treated with TACE
Wang Z, Chapiro J, Schernthaner R, Duran R, Chen R, Geschwind JF, Lin M. Multimodality 3D Tumor Segmentation in HCC Patients Treated with TACE. Academic Radiology 2015, 22: 840-845. PMID: 25863795, PMCID: PMC4464945, DOI: 10.1016/j.acra.2015.03.001.Peer-Reviewed Original ResearchAdultAgedAged, 80 and overAlgorithmsAntibiotics, AntineoplasticCarcinoma, HepatocellularChemoembolization, TherapeuticCone-Beam Computed TomographyDoxorubicinFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalKidney NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedMultidetector Computed TomographyMultimodal ImagingPattern Recognition, AutomatedPrognosisReproducibility of ResultsRetrospective StudiesSensitivity and SpecificitySubtraction TechniqueTreatment Outcome
2012
Phase II Study of Chemoembolization With Drug-Eluting Beads in Patients With Hepatic Neuroendocrine Metastases: High Incidence of Biliary Injury
Bhagat N, Reyes D, Lin M, Kamel I, Pawlik T, Frangakis C, Geschwind J. Phase II Study of Chemoembolization With Drug-Eluting Beads in Patients With Hepatic Neuroendocrine Metastases: High Incidence of Biliary Injury. CardioVascular And Interventional Radiology 2012, 36: 449-459. PMID: 22722717, PMCID: PMC3596485, DOI: 10.1007/s00270-012-0424-y.Peer-Reviewed Original ResearchConceptsTransarterial chemoembolizationTumor sizeNeuroendocrine tumorsHigh incidenceNational Cancer Institute Common Terminology CriteriaEastern Cooperative Oncology Group statusHepatic neuroendocrine metastasesUnderwent percutaneous drainageCommon Terminology CriteriaObjective response ratePhase II studyPhase II trialMultiple small lesionsMethodsInstitutional review board approvalDrug-eluting beadsReview board approvalAlanine amino transferaseTerminology CriteriaAbdominal painBiliary injuryII trialDEB-TACEII studyEASL criteriaPercutaneous drainage