2019
Quantitative Imaging Biomarkers for 90Y Distribution on Bremsstrahlung SPECT After Resin-Based Radioembolization
Schobert I, Chapiro J, Nezami N, Hamm CA, Gebauer B, Lin M, Pollak J, Saperstein L, Schlachter T, Savic LJ. Quantitative Imaging Biomarkers for 90Y Distribution on Bremsstrahlung SPECT After Resin-Based Radioembolization. Journal Of Nuclear Medicine 2019, 60: 1066-1072. PMID: 30655331, PMCID: PMC6681698, DOI: 10.2967/jnumed.118.219691.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiographyBiomarkersCarcinoma, HepatocellularEmbolization, TherapeuticFeasibility StudiesFemaleHumansImaging, Three-DimensionalLiverLiver NeoplasmsMagnetic Resonance ImagingMaleMicrospheresMiddle AgedMultimodal ImagingPrognosisRegression AnalysisRetrospective StudiesTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedTreatment OutcomeYttrium RadioisotopesConceptsNon-HCC patientsTransarterial radioembolizationHepatocellular carcinomaBaseline imagingTumor responseTumor volumeChild-Pugh class B patientsBaseline imaging featuresClass B patientsNormal liver ratiosTotal tumor volumeSPECT/CTContrast-enhanced MRIQuantitative European AssociationMultiphasic contrast-enhanced MRIInstitutional review boardHigh TNRPreprocedural MRIChild-PughB patientsLiver criteriaTumor burdenClinical parametersHepatic malignanciesRetrospective study
2016
A Novel Inherently Radiopaque Bead for Transarterial Embolization to Treat Liver Cancer - A Pre-clinical Study
Duran R, Sharma K, Dreher MR, Ashrafi K, Mirpour S, Lin M, Schernthaner RE, Schlachter TR, Tacher V, Lewis AL, Willis S, Hartog M, Radaelli A, Negussie AH, Wood BJ, Geschwind JF. A Novel Inherently Radiopaque Bead for Transarterial Embolization to Treat Liver Cancer - A Pre-clinical Study. Theranostics 2016, 6: 28-39. PMID: 26722371, PMCID: PMC4679352, DOI: 10.7150/thno.13137.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDisease Models, AnimalDrug Evaluation, PreclinicalEmbolization, TherapeuticFluoroscopyLiver NeoplasmsMicrospheresRabbitsRadiographyStaining and LabelingConceptsEquilibrium water contentDurable suspensionLower equilibrium water contentPhysicomechanical propertiesBead locationSingle shotBead sizeSize distributionSimilar penetrationSimilar size distributionX-ray attenuationBead typesWater contentDeliverabilityBeadsLC beadsHigh densitySuspension timePenetrationCone-beam CTDensityRoMicroshperesSuspensionNon-target arteries
2015
Early survival prediction after intra-arterial therapies: a 3D quantitative MRI assessment of tumour response after TACE or radioembolization of colorectal cancer metastases to the liver
Chapiro J, Duran R, Lin M, Schernthaner R, Lesage D, Wang Z, Savic LJ, Geschwind JF. Early survival prediction after intra-arterial therapies: a 3D quantitative MRI assessment of tumour response after TACE or radioembolization of colorectal cancer metastases to the liver. European Radiology 2015, 25: 1993-2003. PMID: 25636420, PMCID: PMC4458393, DOI: 10.1007/s00330-015-3595-5.Peer-Reviewed Original ResearchConceptsIntra-arterial therapyColorectal liver metastasesTransarterial chemoembolizationPatient survivalHazard ratioLiver metastasesOverall survivalResponse assessmentVolumetric tumour response assessmentCox proportional hazard ratiosMethodsThis retrospective analysisProportional hazard ratiosKaplan-Meier analysisColorectal cancer metastasisTumor response assessmentTumor analysisEarly survival predictionQuantitative MRI assessmentMRI assessmentTumor responseLesion volumeRetrospective analysisMultivariate analysisPatientsPredictive roleThree-Dimensional Quantitative Assessment of Uterine Fibroid Response after Uterine Artery Embolization Using Contrast-Enhanced MR Imaging
Chapiro J, Duran R, Lin M, Werner JD, Wang Z, Schernthaner R, Savic LJ, Lessne ML, Geschwind JF, Hong K. Three-Dimensional Quantitative Assessment of Uterine Fibroid Response after Uterine Artery Embolization Using Contrast-Enhanced MR Imaging. Journal Of Vascular And Interventional Radiology 2015, 26: 670-678.e2. PMID: 25638750, PMCID: PMC4414730, DOI: 10.1016/j.jvir.2014.11.020.Peer-Reviewed Original Research
2013
Can C-Arm Cone-Beam CT Detect a Micro-Embolic Effect After TheraSphere Radioembolization of Neuroendocrine and Carcinoid Liver Metastasis?
Pellerin O, Lin M, Bhagat N, Shao W, Geschwind J. Can C-Arm Cone-Beam CT Detect a Micro-Embolic Effect After TheraSphere Radioembolization of Neuroendocrine and Carcinoid Liver Metastasis? Cancer Biotherapy & Radiopharmaceuticals 2013, 28: 459-465. PMID: 23484809, PMCID: PMC3715773, DOI: 10.1089/cbr.2012.1390.Peer-Reviewed Original ResearchConceptsTumor enhancementHounsfield unitsArterial phaseCapillary levelCarcinoid liver metastasesYttrium-90 microspheresHigh-dose radiationEarly arterial phaseContrast medium injectionC-arm cone-beam CTTheraSphere radioembolizationLiver metastasesNeuroendocrine tumorsHepatic tumorsDelayed phasesRadioembolizationTumor densityMedium injectionTumor attenuationTumor vesselsTumorsTheraSphereEmbolic effectCone-beam CTSignificant decrease
2012
Applications of Imaging Technology in Radiation Research
Lin M, Jackson E. Applications of Imaging Technology in Radiation Research. Radiation Research 2012, 177: 387-397. PMID: 22401349, PMCID: PMC3355534, DOI: 10.1667/rr2696.1.Peer-Reviewed Original ResearchMeSH KeywordsAngiography, Digital SubtractionAnimalsArtifactsContrast MediaDiagnostic ImagingEmbolization, TherapeuticHumansLiver NeoplasmsMagnetic Resonance ImagingMathematicsModels, BiologicalMotionPerfusion ImagingRadiobiologyRadiography, InterventionalStrokeTomography, Spiral ComputedTomography, X-Ray Computed
2011
A comparison of the results of arterial embolization for bleeding and non-bleeding gastroduodenal ulcers
Loffroy R, Lin M, Thompson C, Harsha A, Rao P. A comparison of the results of arterial embolization for bleeding and non-bleeding gastroduodenal ulcers. Acta Radiologica 2011, 52: 1076-1082. PMID: 22006986, DOI: 10.1258/ar.2011.110344.Peer-Reviewed Original ResearchMeSH KeywordsAgedCohort StudiesEmbolization, TherapeuticFemaleFollow-Up StudiesHumansMaleOdds RatioPeptic UlcerPeptic Ulcer HemorrhageRetreatmentSurvival AnalysisTreatment OutcomeConceptsLeft gastric arteryLeft gastroepiploic arteryArterial embolizationGastroduodenal ulcersGastroduodenal arteryClinical successActive contrast extravasationPatients embolizationGastroepiploic arteryAcute bleedingContrast extravasationEndoscopic findingsGastric arteryPatient demographicsAcute hemorrhageTranscatheter embolizationEmbolizationPatientsMortality rateUlcersArteryBleedingComplicationsGroupHemorrhage