LGG-52. Volumetry-based response characterization of recurrent pediatric low-grade gliomas in PNOC clinical Neuro-oncology trials
von Reppert M, Lin M, Bousabarah K, Familiar A, Velasco R, Waanders A, Vossough A, Haddock A, Nicolaides T, Swanson K, Kazerooni A, Kline C, Nabavizadeh A, Haas-Kogan D, Prados M, Rubin J, Mueller S, Aboian M. LGG-52. Volumetry-based response characterization of recurrent pediatric low-grade gliomas in PNOC clinical Neuro-oncology trials. Neuro-Oncology 2022, 24: i100-i100. PMCID: PMC9165161, DOI: 10.1093/neuonc/noac079.364.Peer-Reviewed Original ResearchPediatric low-grade gliomasClinical trialsLow-grade gliomasRANO criteriaResponse assessmentNeuro-oncology trialsSingle-agent everolimusTreatment response analysisCentral imaging reviewInter-reader agreementClinical outcomesTumor sizeImaging reviewCystic componentTreatment responseTumor volumeTrue tumor volumeNovel treatmentsVolumetric assessmentTrial outcomesVolumetric measuresEntire tumorOverall discordanceNeuroradiology practiceTrials