2016
Advanced-stage hepatocellular carcinoma with portal vein thrombosis: conventional versus drug-eluting beads transcatheter arterial chemoembolization
Gorodetski B, Chapiro J, Schernthaner R, Duran R, Lin M, Lee H, Lenis D, Stuart EA, Nonyane BA, Pekurovsky V, Tamrazi A, Gebauer B, Schlachter T, Pawlik TM, Geschwind JF. Advanced-stage hepatocellular carcinoma with portal vein thrombosis: conventional versus drug-eluting beads transcatheter arterial chemoembolization. European Radiology 2016, 27: 526-535. PMID: 27277261, PMCID: PMC5470590, DOI: 10.1007/s00330-016-4445-9.Peer-Reviewed Original ResearchConceptsMedian overall survivalPortal venous thrombosisAdvanced-stage hepatocellular carcinomaConventional TACEDEB-TACEHepatocellular carcinomaOverall survivalAdverse eventsBeads TACEDrug-eluting bead transcatheter arterial chemoembolizationConventional trans-arterial chemoembolizationPropensity scoreDrug-eluting beads TACECommon adverse eventsConclusionOur retrospective studyEqual safety profileChild-Pugh classMethodsThis retrospective analysisPortal vein thrombosisPost-embolization syndromeTranscatheter arterial chemoembolizationStage hepatocellular carcinomaTrans-arterial chemoembolizationSub-group analysisArterial chemoembolization
2013
Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
Tacher V, Lin M, Bhagat N, Jaoudeh N, Radaelli A, Noordhoek N, Carelsen B, Wood B, Geschwind J. Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization. Journal Of Visualized Experiments 2013, 50795. PMID: 24326874, PMCID: PMC3910428, DOI: 10.3791/50795.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaDP-CBCTDual phase CBCTDrug-eluting beadsCone-Beam Computed TomographyRole of CBCTMagnetic resonance imagingDEB-TACETreatment successInvasive therapyLiver tumorsComputed tomographyHCC treatmentInterventional radiologyResonance imagingAngiography suiteDiagnostic imagingSelective therapyCone beamDiagnostic accuracyCBCT techniqueInterventional suiteCarcinomaCBCTTherapy
2012
Phase II Study of Chemoembolization With Drug-Eluting Beads in Patients With Hepatic Neuroendocrine Metastases: High Incidence of Biliary Injury
Bhagat N, Reyes D, Lin M, Kamel I, Pawlik T, Frangakis C, Geschwind J. Phase II Study of Chemoembolization With Drug-Eluting Beads in Patients With Hepatic Neuroendocrine Metastases: High Incidence of Biliary Injury. CardioVascular And Interventional Radiology 2012, 36: 449-459. PMID: 22722717, PMCID: PMC3596485, DOI: 10.1007/s00270-012-0424-y.Peer-Reviewed Original ResearchConceptsTransarterial chemoembolizationTumor sizeNeuroendocrine tumorsHigh incidenceNational Cancer Institute Common Terminology CriteriaEastern Cooperative Oncology Group statusHepatic neuroendocrine metastasesUnderwent percutaneous drainageCommon Terminology CriteriaObjective response ratePhase II studyPhase II trialMultiple small lesionsMethodsInstitutional review board approvalDrug-eluting beadsReview board approvalAlanine amino transferaseTerminology CriteriaAbdominal painBiliary injuryII trialDEB-TACEII studyEASL criteriaPercutaneous drainage