Benign lymph node microenvironment is associated with response to immunotherapy
Toki MI, Kumar D, Ahmed FS, Rimm DL, Xu ML. Benign lymph node microenvironment is associated with response to immunotherapy. Precision Clinical Medicine 2020, 3: 44-53. PMID: 35693430, PMCID: PMC8985791, DOI: 10.1093/pcmedi/pbaa003.Peer-Reviewed Original ResearchBenign lymph nodesLymph nodesT cellsQuantitative immunofluorescenceBenign lymphPD-L1Immune checkpoint blockade therapyMultiplexed quantitative immunofluorescenceHigh expressionCheckpoint blockade therapyMacrophage marker expressionSignificant differencesCytotoxic markersBlockade therapyBenign findingsCancer patientsLymphoid tissueImmune surveillanceTreatment responsePostmortem examinationImmunotherapyProliferation indexSplenic tissueB cellsPatients