Regulation of NKB Pathways and Their Roles in the Control of Kiss1 Neurons in the Arcuate Nucleus of the Male Mouse
Navarro V, Gottsch M, Wu M, García-Galiano D, Hobbs S, Bosch M, Pinilla L, Clifton D, Dearth A, Ronnekleiv O, Braun R, Palmiter R, Tena-Sempere M, Alreja M, Steiner R. Regulation of NKB Pathways and Their Roles in the Control of Kiss1 Neurons in the Arcuate Nucleus of the Male Mouse. Endocrinology 2011, 152: 4265-4275. PMID: 21914775, PMCID: PMC3198996, DOI: 10.1210/en.2011-1143.Peer-Reviewed Original ResearchConceptsGnRH/LH secretionKNDy neuronsKiss1 neuronsGnRH neuronsLH secretionMale miceActions of NKBKiss1-expressing neuronsNegative feedback regulationAdult male miceReceptor-dependent pathwayDynorphin neuronsGonadotropin secretionArcuate nucleusPulsatile secretionDynorphin ANegative feedback effectNKB receptorNKBNeuronsSecretionFeedback regulationKiss1SenktidePutative role