Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro
Escribano J, Alonso G, Coca-Prados M, Fernández J. Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro. Cancer Letters 1996, 100: 23-30. PMID: 8620447, DOI: 10.1016/0304-3835(95)04067-6.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Agents, PhytogenicCarotenoidsCell DivisionCondimentsCyclohexenesDrug Screening Assays, AntitumorGlucosidesHeLa CellsHumansPlant ExtractsPlants, EdibleTerpenesConceptsExtract of saffronCytotoxic effectsCell growth inhibitionCancer therapeutic agentsHuman tumor cellsHuman cancer cellsPyknotic nucleiInhibitory growth effectTherapeutic agentsTumor cellsCancer cellsEthanolic extractApoptosis inductionCrocinGrowth inhibitionReduced cytoplasmCell growthCellsCrocetinCell shrinkageDosesHeLa cells