2001
PGE2, Ca2+, and cAMP mediate ATP activation of Cl− channels in pigmented ciliary epithelial cells
Fleischhauer J, Mitchell C, Peterson-Yantorno K, Coca-Prados M, Civan M. PGE2, Ca2+, and cAMP mediate ATP activation of Cl− channels in pigmented ciliary epithelial cells. American Journal Of Physiology - Cell Physiology 2001, 281: c1614-c1623. PMID: 11600425, DOI: 10.1152/ajpcell.2001.281.5.c1614.Peer-Reviewed Original ResearchConceptsPigmented ciliary epithelial cellsCiliary epithelial cellsCl- channelsEpithelial cellsPE cellsCl- channel activityAction of nucleotidesProtein kinaseNonpigmented ciliary epithelial cellsSecond messengerCell sortingChannel activityATP activationElectronic cell sortingATPSequential cascadeChannel activationNucleotidesP2Y receptorsPatch clampingATP assayATP releaseCellsMicroM ATPCAMP
1983
Protein Phosphorylation in Cultured Human Ciliary Epithelia in Response to Activators of Adenylate Cyclase, Cyclic AMP and Analogues
Coca-Prados M, Kondo K, Sears M. Protein Phosphorylation in Cultured Human Ciliary Epithelia in Response to Activators of Adenylate Cyclase, Cyclic AMP and Analogues. 1983, 1-6. DOI: 10.1007/978-3-642-69096-9_1.Peer-Reviewed Original ResearchSpecific substrate proteinsDiverse cell systemsProtein kinase activityState of phosphorylationCyclic AMPSubstrate proteinsProtein phosphorylationEndogenous proteinsKinase activitySecond messengerHuman ciliary epitheliumPhosphorylationMembrane permeabilityProteinCell systemAdenylate cyclaseCiliary epitheliumBiologic responseMessengerActivatorAMPCyclaseResponse