2022
Maternal Diabetes in Youth-Onset Type 2 Diabetes Is Associated With Progressive Dysglycemia and Risk of Complications
Shah R, Chernausek S, ghormli L, Geffner M, Keady J, Kelsey M, Farrell R, Tesfaldet B, Tryggestad J, Van Name M, Isganaitis E. Maternal Diabetes in Youth-Onset Type 2 Diabetes Is Associated With Progressive Dysglycemia and Risk of Complications. The Journal Of Clinical Endocrinology & Metabolism 2022, 108: 1120-1131. PMID: 36446741, PMCID: PMC10306086, DOI: 10.1210/clinem/dgac663.Peer-Reviewed Original ResearchConceptsYouth-onset type 2 diabetesType 2 diabetesMaternal diabetesHeart rate variabilityGlomerular hyperfiltrationParental diabetesGlycemic controlRate variabilityFuture cardiometabolic diseaseParental diabetes historyYouth-onset T2D.Lower heart rate variabilityRisk of complicationsWorse glycemic controlΒ-cell functionRace/ethnicityDiabetes historyCardiometabolic diseasesDiabetes outcomesPrenatal exposureUS cohortGlycemic outcomesRisk factorsDisease progressionUS Centers
2021
19-OR: Maternal Diabetes Is Associated with Adverse Diabetes Characteristics and Accelerated Onset of Complications in Youth with Type 2 Diabetes (T2D) in TODAY
ISGANAITIS E, SHAH R, CHERNAUSEK S, FARRELL R, GEFFNER M, KEADY J, KELSEY M, TESFALDET B, TRYGGESTAD J, VAN NAME M. 19-OR: Maternal Diabetes Is Associated with Adverse Diabetes Characteristics and Accelerated Onset of Complications in Youth with Type 2 Diabetes (T2D) in TODAY. Diabetes 2021, 70 DOI: 10.2337/db21-19-or.Peer-Reviewed Original ResearchGlycemic controlAccelerated onsetDaiichi SankyoAdverse diabetes outcomesFuture cardiometabolic healthNegative islet autoantibodiesYouth-onset T2D.Type 2 diabetesMothers of participantsNovo NordiskSuccessive NN intervalsHeart rate variabilityGlomerular hyperfiltrationIslet autoantibodiesCardiometabolic healthDiabetes statusMaternal diabetesKidney diseaseDiabetes careDM diagnosisDohme Corp.Diabetes outcomesPrenatal exposureDiabetes characteristicsDiabetic retinopathy