Low temperature and temperature decline increase acute aortic dissection risk and burden: A nationwide case crossover analysis at hourly level among 40,270 patients
Zhang Q, Peng L, Hu J, Li H, Jiang Y, Fang W, Yan H, Chen J, Wang W, Xiang D, Su X, Yu B, Wang Y, Xu Y, Wang L, Li C, Chen Y, Zhao D, Ge W, Bell M, Gasparrini A, Ge J, Huo Y, Kan H. Low temperature and temperature decline increase acute aortic dissection risk and burden: A nationwide case crossover analysis at hourly level among 40,270 patients. The Lancet Regional Health - Western Pacific 2022, 28: 100562. PMID: 35991537, PMCID: PMC9386641, DOI: 10.1016/j.lanwpc.2022.100562.Peer-Reviewed Original ResearchAcute aortic dissectionAAD onsetDisease burdenAAD casesLife-threatening cardiovascular emergencyTime-stratified case-crossover studyAortic dissection riskCorresponding disease burdenGreat public health significanceModifiable risk factorsConditional logistic regressionCase-crossover studyLarge nationwide studyCase-crossover analysisMedical Research Council UKPublic health significanceAortic dissectionAssociation of temperatureCardiovascular emergenciesResearch Council UKRisk factorsAttributable fractionExposure-response curvesCumulative relative riskRelative risk