Platelet activation in cystic fibrosis
O'Sullivan BP, Linden MD, Frelinger AL, Barnard MR, Spencer-Manzon M, Morris JE, Salem RO, Laposata M, Michelson AD. Platelet activation in cystic fibrosis. Blood 2005, 105: 4635-4641. PMID: 15705796, DOI: 10.1182/blood-2004-06-2098.Peer-Reviewed Original ResearchMeSH KeywordsAdenylyl CyclasesAdolescentAdultAlprostadilAnti-Inflammatory Agents, Non-SteroidalArachidonic AcidBlood PlateletsBlotting, WesternCase-Control StudiesCell MembraneChildCyclic AMPCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorFatty AcidsGenotypeHumansIbuprofenInflammationLeukocytesMonocytesNeutrophilsPlatelet ActivationP-SelectinReverse Transcriptase Polymerase Chain ReactionRNA, MessengerThromboxane A2Time FactorsVitamin EConceptsCystic fibrosisCF patientsCyclic adenosine monophosphatePlatelet activationPlatelet surface P-selectinMonocyte-platelet aggregationNeutrophil-platelet aggregationCystic fibrosis transmembrane conductance regulatorLeukocyte-platelet aggregatesSurface P-selectinLung inflammationPlatelet hyperreactivityPlatelet reactivityPlatelet responsivenessPolymerase chain reactionHealthy controlsPlatelet functionP-selectinNormal platelets