2020
Chapter 68 Lung tissue engineering
Raredon M, Yuan Y, Niklason L. Chapter 68 Lung tissue engineering. 2020, 1273-1285. DOI: 10.1016/b978-0-12-818422-6.00070-8.ChaptersTissue homeostasisTissue-engineered lungsExtracellular matrixHomeostatic levelsPulmonary regenerationCell populationsGas exchangeRegeneration of lungTissue unitsFunctional unitsPrecise mixtureRegenerationTissue engineeringProteinHomeostasisBarrier integrityCellsLung tissue engineeringTissue damageTranslationBroad overview
2019
Single-cell connectomic analysis of adult mammalian lungs
Raredon MSB, Adams TS, Suhail Y, Schupp JC, Poli S, Neumark N, Leiby KL, Greaney AM, Yuan Y, Horien C, Linderman G, Engler AJ, Boffa DJ, Kluger Y, Rosas IO, Levchenko A, Kaminski N, Niklason LE. Single-cell connectomic analysis of adult mammalian lungs. Science Advances 2019, 5: eaaw3851. PMID: 31840053, PMCID: PMC6892628, DOI: 10.1126/sciadv.aaw3851.Peer-Reviewed Original ResearchConceptsTissue homeostasisMammalian lungSingle-cell RNA sequencing techniquesAdult mammalian lungRNA sequencing techniquesCell-cell interactionsSequencing techniquesKey pathwaysAlveolar type IFunctional roleCell typesCell populationsRegenerative medicineHomeostatic mechanismsHomeostasisFine architectureFunctional lung tissueIncomplete understandingMajor roleType ITissueRegulationPathwayAlveolar cell populationsDistal lung