2015
Presence and Number of Lymph Node Metastases Are Associated With Compromised Survival for Patients Younger Than Age 45 Years With Papillary Thyroid Cancer
Adam MA, Pura J, Goffredo P, Dinan MA, Reed SD, Scheri RP, Hyslop T, Roman SA, Sosa JA. Presence and Number of Lymph Node Metastases Are Associated With Compromised Survival for Patients Younger Than Age 45 Years With Papillary Thyroid Cancer. Journal Of Clinical Oncology 2015, 33: 2370-2375. PMID: 26077238, DOI: 10.1200/jco.2014.59.8391.Peer-Reviewed Original ResearchConceptsCervical lymph node metastasisAge 45 yearsLymph node metastasisPapillary thyroid cancerMetastatic lymph nodesAmerican Joint CommitteeOverall survivalNode metastasisMetastatic nodesLymph nodesNodal metastasisThyroid cancerJoint CommitteeAssociation of OSPatients age 45 yearsNational Cancer Data BaseCurrent American Joint CommitteeMore positive nodesLow-risk diseasePresence of lymphAdditional mortality riskPositive nodesPreoperative screeningAdult patientsSEER databaseImpact of Extent of Surgery on Survival for Papillary Thyroid Cancer Patients Younger Than 45 Years
Adam M, Pura J, Goffredo P, Dinan MA, Hyslop T, Reed SD, Scheri RP, Roman SA, Sosa JA. Impact of Extent of Surgery on Survival for Papillary Thyroid Cancer Patients Younger Than 45 Years. The Journal Of Clinical Endocrinology & Metabolism 2015, 100: 115-121. PMID: 25337927, PMCID: PMC5399499, DOI: 10.1210/jc.2014-3039.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancer patientsTotal thyroidectomyOverall survivalThyroid cancer patientsImpact of extentYears of ageCancer patientsNational Cancer Data BaseUnadjusted overall survivalLymph node diseaseExtent of resectionEnd Results (SEER) datasetAdult patientsClinical characteristicsExcellent prognosisNode diseasePathologic factorsImproved survivalThyroid lobectomyTumor sizeCurrent guidelinesMultivariable modelingLobectomyMAIN OUTCOMEThyroidectomy
2014
Impact of Extent of Surgery on Survival in Patients with Small Nonfunctional Pancreatic Neuroendocrine Tumors in the United States
Gratian L, Pura J, Dinan M, Roman S, Reed S, Sosa JA. Impact of Extent of Surgery on Survival in Patients with Small Nonfunctional Pancreatic Neuroendocrine Tumors in the United States. Annals Of Surgical Oncology 2014, 21: 3515-3521. PMID: 24841347, PMCID: PMC4510956, DOI: 10.1245/s10434-014-3769-4.Peer-Reviewed Original ResearchConceptsNonfunctional pancreatic neuroendocrine tumorsPancreatic neuroendocrine tumorsExtent of surgerySmall Nonfunctional Pancreatic Neuroendocrine TumorsFive-year OSOverall survivalMalignant potentialNeuroendocrine tumorsNational Cancer Data BaseLymph node dissectionLymph node resectionKaplan-Meier analysisType of surgeryLog-rank testUncertain malignant potentialImpact of extentNode dissectionNode resectionTotal pancreatectomyPatient characteristicsRegional lymphRegional lymphadenectomySurgical resectionImproved survivalDistant metastasis