2023
Disparities in immune and targeted therapy utilization for older US patients with metastatic renal cell carcinoma
Chow R, Long J, Hassan S, Wheeler S, Spees L, Leapman M, Hurwitz M, McManus H, Gross C, Dinan M. Disparities in immune and targeted therapy utilization for older US patients with metastatic renal cell carcinoma. JNCI Cancer Spectrum 2023, 7: pkad036. PMID: 37202354, PMCID: PMC10276895, DOI: 10.1093/jncics/pkad036.Peer-Reviewed Original ResearchConceptsOral anticancer agentsTherapy utilizationMedicare beneficiariesNon-Hispanic white raceMetastatic renal cell carcinomaNon-Hispanic black raceOlder US patientsUS Medicare beneficiariesRenal cell carcinomaLogistic regression modelsTherapy receiptMultivariable adjustmentSystemic therapyMale sexUS patientsCell carcinomaStudy criteriaBlack raceFemale sexPatient raceWhite raceImmunotherapyOutcomes persistSexPatients
2020
Disparities in utilization of oral anticancer agents and related costs in elderly patients with metastatic renal cell carcinoma in the United States.
Wilson L, Spees L, Pritchard J, Greiner M, Scales C, Baggett C, Kaye D, George D, Zhang T, Wheeler S, Dinan M. Disparities in utilization of oral anticancer agents and related costs in elderly patients with metastatic renal cell carcinoma in the United States. Journal Of Clinical Oncology 2020, 38: 106-106. DOI: 10.1200/jco.2020.38.29_suppl.106.Peer-Reviewed Original ResearchMetastatic renal cell carcinomaOral anticancer agentsRenal cell carcinomaPatient characteristicsCell carcinomaManagement of mRCCSEER-Medicare patientsMultivariable-adjusted modelsMajority of patientsPatient-level characteristicsAnticancer agentsMedicare Part D benefitPart D benefitSurvival persistCertain comorbiditiesElderly patientsMultivariable adjustmentMarried patientsMetastatic diagnosisRace/ethnicity categoriesAdvanced ageInclusion criteriaHispanic ethnicityPatientsPocket spending
2015
Knowledge of pathologically versus clinically negative lymph nodes is associated with reduced use of radioactive iodine post-thyroidectomy for low-risk papillary thyroid cancer
Ruel E, Thomas S, Dinan MA, Perkins JM, Roman SA, Sosa JA. Knowledge of pathologically versus clinically negative lymph nodes is associated with reduced use of radioactive iodine post-thyroidectomy for low-risk papillary thyroid cancer. Endocrine 2015, 52: 579-586. PMID: 26708045, PMCID: PMC4880494, DOI: 10.1007/s12020-015-0826-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCarcinomaCarcinoma, PapillaryCombined Modality TherapyDatabases, FactualFemaleHumansIodine RadioisotopesKnowledgeLymph NodesLymphatic MetastasisMaleMiddle AgedPostoperative PeriodPrognosisRadiotherapy DosageRisk FactorsSurvival AnalysisThyroid Cancer, PapillaryThyroid NeoplasmsThyroidectomyConceptsNegative lymph nodesPapillary thyroid cancerLow-risk papillary thyroid cancerLymph nodesCN0 patientsRAI useThyroid cancerPostoperative radioactive iodine administrationTrue nodal statusExcised lymph nodesLow-risk patientsLymph node statusRadioactive iodine administrationNegative surgical marginsOdds of receiptSurgical pathology specimensCut-point analysisPN0 patientsPN0 statusPostoperative RAIRAI administrationCervical lymphMultivariable adjustmentTotal thyroidectomyNodal statusMinimally Invasive Versus Open Pancreaticoduodenectomy for Cancer
Adam MA, Choudhury K, Dinan MA, Reed SD, Scheri RP, Blazer DG, Roman SA, Sosa JA. Minimally Invasive Versus Open Pancreaticoduodenectomy for Cancer. Annals Of Surgery 2015, 262: 372-377. PMID: 26158612, DOI: 10.1097/sla.0000000000001055.Peer-Reviewed Original ResearchConceptsShort-term outcomesOpen pancreaticoduodenectomyMajority of hospitalsOpen surgeryInvasive Versus Open PancreaticoduodenectomyNational practice patternsSingle institutional experiencePositive surgical marginsLength of stayNeuroendocrine tumor diagnosisMultivariable adjustmentAdult patientsLymph nodesSurgical marginsInvasive pancreaticoduodenectomyOpen procedurePractice patternsInstitutional experiencePancreaticoduodenectomyMultivariable modelingMortality ratePatientsPatient safetyMIPDTumor diagnosis
2014
Extent of Surgery for Papillary Thyroid Cancer Is Not Associated With Survival
Adam MA, Pura J, Gu L, Dinan MA, Tyler DS, Reed SD, Scheri R, Roman SA, Sosa JA. Extent of Surgery for Papillary Thyroid Cancer Is Not Associated With Survival. Annals Of Surgery 2014, 260: 601-607. PMID: 25203876, PMCID: PMC4532384, DOI: 10.1097/sla.0000000000000925.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerExtent of surgeryTotal thyroidectomyOverall survivalTumor sizeDistant metastasisThyroid cancerSurvival advantagePTC tumorsRadioactive iodine treatmentLarge contemporary cohortOverall survival advantageUnderwent total thyroidectomyProportional hazards modelPresence of nodalMultivariable adjustmentAdult patientsClinical factorsContemporary cohortMultifocal diseaseAbsolute indicationMale sexTumors 1.0Black racePTC patients