Androgen deprivation therapy (ADT) and cardiovascular mortality (CVD) in men with early-stage prostate cancer (PC) receiving curative radiation therapy (RT).
Hanlon A, Fleming S, Hamilton A, Dinan M, Melloni C, Harrison M, Khouri M, Wu X, Wilson J, Lipscomb J, Cress R, Anderson R, Kimmick G. Androgen deprivation therapy (ADT) and cardiovascular mortality (CVD) in men with early-stage prostate cancer (PC) receiving curative radiation therapy (RT). Journal Of Clinical Oncology 2018, 36: 127-127. DOI: 10.1200/jco.2018.36.7_suppl.127.Peer-Reviewed Original ResearchUse of ADTAndrogen deprivation therapyProstate cancerRadiation therapyAdult Comorbidity Evaluation-27National Death Index dataPopulation-based cancer registriesEarly-stage prostate cancerAge 67.7 yearsCV risk factorsDefinitive radiation therapyDeath Index dataRisk of CVDCurative radiation therapyGleason score 3Hazard of deathCause of deathProstate cancer patternsHigher socioeconomic statusRace/ethnicityCV deathCVD equivalentDeprivation therapyHigher CVDCV disease