2024
Cortical structure and subcortical volumes in conduct disorder: a coordinated analysis of 15 international cohorts from the ENIGMA-Antisocial Behavior Working Group
Gao Y, Staginnus M, Group E, Gao Y, Staginnus M, Townend S, Arango C, Bajaj S, Banaschewski T, Barker E, Benegal V, Berluti K, Bernhard A, Blair R, Boateng C, Bokde A, Brandeis D, Buitelaar J, Burt S, Cardinale E, Castro-Fornieles J, Chen H, Chen X, Chester S, Colins O, Cornwell H, Craig M, Cubillo A, Desrivieres S, Díaz D, Dietrich A, Dong D, Dykstra A, Franke B, Freitag C, Glennon J, Gonzalez-Madruga K, Hagan C, Hoekstra P, Holla B, Hyde L, Ibrahim K, Jabeen N, Jackson R, Jiang Y, Kohls G, Konrad K, Kypta-Vivanco A, Lamers K, Ma R, Marsh A, Martinelli A, Martinot J, Michalska K, Ming Q, Minosse S, Mitchell C, Monk C, Murphy D, Mycue L, Naaijen J, Oosterling M, Passamonti L, Pauli R, Alonso M, Phillips H, Ploe M, Raschle N, Roberts R, Rogers J, Rosa-Justicia M, Sagar-Ouriaghli I, Schulze U, Schumann G, Sethi A, Smaragdi A, Sonuga-Barke E, Stadler C, Stevens M, Sukhodolsky D, Sully K, Sun X, Toschi N, Townsend C, van der Wee N, Vermeiren R, Viding E, Wang X, Westerman H, Wu Q, Yao S, Zhang J, Zhou J, Zhou J, Jahanshad N, Thomopoulos S, Ching C, Kang M, Thompson P, Klapwijk E, Pine D, Baskin-Sommers A, Cecil C, Aghajani M, Walton E, Fairchild G, De Brito S. Cortical structure and subcortical volumes in conduct disorder: a coordinated analysis of 15 international cohorts from the ENIGMA-Antisocial Behavior Working Group. The Lancet Psychiatry 2024, 11: 620-632. PMID: 39025633, DOI: 10.1016/s2215-0366(24)00187-1.Peer-Reviewed Original ResearchConceptsGroup-by-age interactionCallous-unemotional traitsConduct disorder groupConduct disorderBrain structural alterationsSubcortical volumesDisorder groupDiagnosis of conduct disorderCaudal anterior cingulate cortexAnalysis of structural MRI dataCortical thicknessT1-weighted MRI brain scansBrain structural correlatesAnterior cingulate cortexSuperior temporal sulcusStructural MRI dataAssess group differencesMRI brain scansNucleus accumbensADHD comorbidityCingulate cortexDisorder subtypesSmaller amygdalaBrain alterationsTemporal sulcus
2020
Subcortical Brain Volume, Regional Cortical Thickness, and Cortical Surface Area Across Disorders: Findings From the ENIGMA ADHD, ASD, and OCD Working Groups
Boedhoe PSW, van Rooij D, Hoogman M, Twisk JWR, Schmaal L, Abe Y, Alonso P, Ameis SH, Anikin A, Anticevic A, Arango C, Arnold PD, Asherson P, Assogna F, Auzias G, Banaschewski T, Baranov A, Batistuzzo MC, Baumeister S, Baur-Streubel R, Behrmann M, Bellgrove MA, Benedetti F, Beucke JC, Biederman J, Bollettini I, Bose A, Bralten J, Bramati IE, Brandeis D, Brem S, Brennan BP, Busatto GF, Calderoni S, Calvo A, Calvo R, Castellanos FX, Cercignani M, Chaim-Avancini TM, Chantiluke KC, Cheng Y, Cho KIK, Christakou A, Coghill D, Conzelmann A, Cubillo AI, Dale AM, Dallaspezia S, Daly E, Denys D, Deruelle C, Di Martino A, Dinstein I, Doyle AE, Durston S, Earl EA, Ecker C, Ehrlich S, Ely BA, Epstein JN, Ethofer T, Fair DA, Fallgatter AJ, Faraone SV, Fedor J, Feng X, Feusner JD, Fitzgerald J, Fitzgerald KD, Fouche JP, Freitag CM, Fridgeirsson EA, Frodl T, Gabel MC, Gallagher L, Gogberashvili T, Gori I, Gruner P, Gürsel DA, Haar S, Haavik J, Hall GB, Harrison NA, Hartman CA, Heslenfeld DJ, Hirano Y, Hoekstra PJ, Hoexter MQ, Hohmann S, Høvik MF, Hu H, Huyser C, Jahanshad N, Jalbrzikowski M, James A, Janssen J, Jaspers-Fayer F, Jernigan TL, Kapilushniy D, Kardatzki B, Karkashadze G, Kathmann N, Kaufmann C, Kelly C, Khadka S, King JA, Koch K, Kohls G, Konrad K, Kuno M, Kuntsi J, Kvale G, Kwon JS, Lázaro L, Lera-Miguel S, Lesch KP, Hoekstra L, Liu Y, Lochner C, Louza MR, Luna B, Lundervold AJ, Malpas CB, Marques P, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Mattos P, McCarthy H, McGrath J, Mehta MA, Menchón JM, Mennes M, Martinho MM, Moreira PS, Morer A, Morgado P, Muratori F, Murphy CM, Murphy DGM, Nakagawa A, Nakamae T, Nakao T, Namazova-Baranova L, Narayanaswamy JC, Nicolau R, Nigg JT, Novotny SE, Nurmi EL, Weiss EO, O'Gorman Tuura RL, O'Hearn K, O'Neill J, Oosterlaan J, Oranje B, Paloyelis Y, Parellada M, Pauli P, Perriello C, Piacentini J, Piras F, Piras F, Plessen KJ, Puig O, Ramos-Quiroga JA, Reddy YCJ, Reif A, Reneman L, Retico A, Rosa PGP, Rubia K, Rus OG, Sakai Y, Schrantee A, Schwarz L, Schweren LJS, Seitz J, Shaw P, Shook D, Silk TJ, Simpson HB, Skokauskas N, Soliva Vila JC, Solovieva A, Soreni N, Soriano-Mas C, Spalletta G, Stern ER, Stevens MC, Stewart SE, Sudre G, Szeszko PR, Tamm L, Taylor MJ, Tolin DF, Tosetti M, Tovar-Moll F, Tsuchiyagaito A, van Erp TGM, van Wingen GA, Vance A, Venkatasubramanian G, Vilarroya O, Vives-Gilabert Y, von Polier GG, Walitza S, Wallace GL, Wang Z, Wolfers T, Yoncheva YN, Yun JY, Zanetti MV, Zhou F, Ziegler GC, Zierhut KC, Zwiers MP, Thompson P, Stein D, Buitelaar J, Franke B, van den Heuvel O. Subcortical Brain Volume, Regional Cortical Thickness, and Cortical Surface Area Across Disorders: Findings From the ENIGMA ADHD, ASD, and OCD Working Groups. American Journal Of Psychiatry 2020, 177: 834-843. PMID: 32539527, PMCID: PMC8296070, DOI: 10.1176/appi.ajp.2020.19030331.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderAutism spectrum disorderObsessive-compulsive disorderDeficit hyperactivity disorderFrontal cortexCommon neurodevelopmental disorderStandardized processing protocolsStructural brain differencesCortical thickness differencesWhole-brain MRI dataCortical thicknessHyperactivity disorderCortical surface areaSpectrum disorderBrain differencesSmaller hippocampal volumesDifferent age groupsRegional cortical thicknessSubcortical brain volumesClinical groupsStructural brainSmaller intracranial volumeShared differenceNeurodevelopmental disordersHippocampal differences
2016
Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis
Boedhoe PS, Schmaal L, Abe Y, Ameis SH, Arnold PD, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Bose A, Brem S, Calvo A, Cheng Y, Cho KI, Dallaspezia S, Denys D, Fitzgerald KD, Fouche JP, Giménez M, Gruner P, Hanna GL, Hibar DP, Hoexter MQ, Hu H, Huyser C, Ikari K, Jahanshad N, Kathmann N, Kaufmann C, Koch K, Kwon JS, Lazaro L, Liu Y, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minuzzi L, Nakamae T, Nakao T, Narayanaswamy JC, Piras F, Piras F, Pittenger C, Reddy YC, Sato JR, Simpson HB, Soreni N, Soriano-Mas C, Spalletta G, Stevens MC, Szeszko PR, Tolin DF, Venkatasubramanian G, Walitza S, Wang Z, van Wingen GA, Xu J, Xu X, Yun JY, Zhao Q, Thompson P, Stein D, van den Heuvel O, Abe Y, Alonso P, Ameis S, Arnold P, Bargalló N, Batistuzzo M, Benedetti F, Beucke J, Boedhoe P, Bollettini I, Bose A, Brem S, Busatto G, Calvo A, Calvo R, Cath D, Cheng Y, Cho K, Dallaspezia S, de Vries F, de Wit S, Denys D, Fang Y, Fitzgerald K, Fontaine M, Fouche J, Giménez M, Gruner P, Hanna G, Hibar D, Hoexter M, Hu H, Huyser C, Ikari K, Jahanshad N, Kathmann N, Kaufmann C, Khadka S, Koch K, Kwon J, Lazaro L, Liu Y, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón J, Miguel E, Minuzzii L, Morer A, Nakamae T, Nakao T, Narayanaswamy J, Piras F, Piras F, Pittenger C, Reddy Y, Sato J, Simpson H, Schmaal L, Soreni N, Soriano-Mas C, Spalletta G, Stein D, Stevens M, Szeszko P, Thompson P, Tolin D, Veltman D, Venkatasubramanian G, van den Heuvel O, van der Werf Y, van Wingen G, Walitza S, Wang Z, Xu J, Xu X, Yun J, Zhao Q. Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis. American Journal Of Psychiatry 2016, 174: 60-69. PMID: 27609241, PMCID: PMC5344782, DOI: 10.1176/appi.ajp.2016.16020201.Peer-Reviewed Original ResearchConceptsAdult obsessive-compulsive disorderObsessive-compulsive disorderOCD patientsLarger thalamic volumesSubcortical volume alterationsSmaller hippocampal volumesAdult OCD patientsPediatric obsessive-compulsive disorderPotential modulating effectSubcortical brain volumesLimited statistical powerPallidum volumeClinical characteristicsAdult patientsPediatric patientsMean ageThalamic volumeControl subjectsPediatric controlsSubcortical abnormalitiesIllness profileHippocampal volumeHealthy subjectsNeurodevelopmental alterationsPatients