2024
Cortical structure and subcortical volumes in conduct disorder: a coordinated analysis of 15 international cohorts from the ENIGMA-Antisocial Behavior Working Group
Gao Y, Staginnus M, Group E, Gao Y, Staginnus M, Townend S, Arango C, Bajaj S, Banaschewski T, Barker E, Benegal V, Berluti K, Bernhard A, Blair R, Boateng C, Bokde A, Brandeis D, Buitelaar J, Burt S, Cardinale E, Castro-Fornieles J, Chen H, Chen X, Chester S, Colins O, Cornwell H, Craig M, Cubillo A, Desrivieres S, Díaz D, Dietrich A, Dong D, Dykstra A, Franke B, Freitag C, Glennon J, Gonzalez-Madruga K, Hagan C, Hoekstra P, Holla B, Hyde L, Ibrahim K, Jabeen N, Jackson R, Jiang Y, Kohls G, Konrad K, Kypta-Vivanco A, Lamers K, Ma R, Marsh A, Martinelli A, Martinot J, Michalska K, Ming Q, Minosse S, Mitchell C, Monk C, Murphy D, Mycue L, Naaijen J, Oosterling M, Passamonti L, Pauli R, Alonso M, Phillips H, Ploe M, Raschle N, Roberts R, Rogers J, Rosa-Justicia M, Sagar-Ouriaghli I, Schulze U, Schumann G, Sethi A, Smaragdi A, Sonuga-Barke E, Stadler C, Stevens M, Sukhodolsky D, Sully K, Sun X, Toschi N, Townsend C, van der Wee N, Vermeiren R, Viding E, Wang X, Westerman H, Wu Q, Yao S, Zhang J, Zhou J, Zhou J, Jahanshad N, Thomopoulos S, Ching C, Kang M, Thompson P, Klapwijk E, Pine D, Baskin-Sommers A, Cecil C, Aghajani M, Walton E, Fairchild G, De Brito S. Cortical structure and subcortical volumes in conduct disorder: a coordinated analysis of 15 international cohorts from the ENIGMA-Antisocial Behavior Working Group. The Lancet Psychiatry 2024, 11: 620-632. PMID: 39025633, DOI: 10.1016/s2215-0366(24)00187-1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmygdalaBrainCerebral CortexChildCohort StudiesConduct DisorderFemaleHumansMagnetic Resonance ImagingMaleOrgan SizeYoung AdultConceptsGroup-by-age interactionCallous-unemotional traitsConduct disorder groupConduct disorderBrain structural alterationsSubcortical volumesDisorder groupDiagnosis of conduct disorderCaudal anterior cingulate cortexAnalysis of structural MRI dataCortical thicknessT1-weighted MRI brain scansBrain structural correlatesAnterior cingulate cortexSuperior temporal sulcusStructural MRI dataAssess group differencesMRI brain scansNucleus accumbensADHD comorbidityCingulate cortexDisorder subtypesSmaller amygdalaBrain alterationsTemporal sulcus
2022
Associations of medication with subcortical morphology across the lifespan in OCD: Results from the international ENIGMA Consortium
Ivanov I, Boedhoe PSW, Abe Y, Alonso P, Ameis SH, Arnold PD, Balachander S, Baker JT, Banaj N, Bargalló N, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Brem S, Brennan BP, Buitelaar J, Calvo R, Cheng Y, Cho KIK, Dallaspezia S, Denys D, Diniz JB, Ely BA, Feusner JD, Ferreira S, Fitzgerald KD, Fontaine M, Gruner P, Hanna GL, Hirano Y, Hoexter MQ, Huyser C, Ikari K, James A, Jaspers-Fayer F, Jiang H, Kathmann N, Kaufmann C, Kim M, Koch K, Kwon JS, Lázaro L, Liu Y, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minuzzi L, Morer A, Morgado P, Nakagawa A, Nakamae T, Nakao T, Narayanaswamy JC, Nurmi EL, Oh S, Perriello C, Piacentini JC, Picó-Pérez M, Piras F, Piras F, Reddy YCJ, Manrique DR, Sakai Y, Shimizu E, Simpson HB, Soreni N, Soriano-Mas C, Spalletta G, Stern ER, Stevens MC, Stewart SE, Szeszko PR, Tolin DF, van Rooij D, Veltman DJ, van der Werf YD, van Wingen GA, Venkatasubramanian G, Walitza S, Wang Z, Watanabe A, Wolters LH, Xu X, Yun JY, Zarei M, Zhang F, Zhao Q, Jahanshad N, Thomopoulos SI, Thompson PM, Stein DJ, van den Heuvel OA, O'Neill J, Group T, Poletti S, Fridgeirsson E, Ikuta T, de Wit S, Vriend C, Kasprzak S, Kuno M, Takahashi J, Miguel E, Shavitt R, Hough M, Pariente J, Ortiz A, Bertolín S, Real E, Segalàs C, Moreira P, Sousa N, Narumoto J, Yamada K, Tang J, Fouche J, Kim T, Choi S, Ha M, Park S. Associations of medication with subcortical morphology across the lifespan in OCD: Results from the international ENIGMA Consortium. Journal Of Affective Disorders 2022, 318: 204-216. PMID: 36041582, DOI: 10.1016/j.jad.2022.08.084.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderUnmedicated patientsOlder adultsAssociation of medicationVolumes of putamenSubcortical brain structuresReuptake inhibitorsVentricular hypertrophyHippocampal atrophyMedicated patientsPsychotropic medicationsTherapeutic responseHippocampal volumeStriatal volumeSubcortical nucleiPatientsPsychotic disordersAntipsychoticsSubcortical morphologyStructural MRINormal agingBrain structuresBenzodiazepinesOCD patientsENIGMA consortiumStructural language impairment in Autism Spectrum Disorder versus Loss of Autism Diagnosis: Behavioral and neural characteristics
Larson C, Rivera-Figueroa K, Thomas H, Fein D, Stevens M, Eigsti I. Structural language impairment in Autism Spectrum Disorder versus Loss of Autism Diagnosis: Behavioral and neural characteristics. NeuroImage Clinical 2022, 34: 103043. PMID: 35567947, PMCID: PMC9112023, DOI: 10.1016/j.nicl.2022.103043.Peer-Reviewed Original ResearchMeSH KeywordsAutism Spectrum DisorderAutistic DisorderBrainHumansLanguageLanguage Development DisordersMagnetic Resonance ImagingConceptsStructural language impairmentAutism spectrum disorderLanguage impairmentSpectrum disorderAutism diagnosisLanguage-related brain regionsStructural language abilitiesStructural language difficultiesLeft hemisphere lateralizationFunctional MRI resultsFunctional neuroimaging methodsRecalling SentencesHemisphere lateralizationLanguage abilityNeural specializationADHD symptomsSocial abilitiesASD symptomsLanguage difficultiesLanguage functionNeural characteristicsNeuroimaging methodsGroup differencesBrain regionsOmnibus measureThe thalamus and its subnuclei—a gateway to obsessive-compulsive disorder
Weeland CJ, Kasprzak S, de Joode NT, Abe Y, Alonso P, Ameis SH, Anticevic A, Arnold PD, Balachander S, Banaj N, Bargallo N, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Brecke V, Brem S, Cappi C, Cheng Y, Cho KIK, Costa DLC, Dallaspezia S, Denys D, Eng GK, Ferreira S, Feusner JD, Fontaine M, Fouche JP, Grazioplene RG, Gruner P, He M, Hirano Y, Hoexter MQ, Huyser C, Hu H, Jaspers-Fayer F, Kathmann N, Kaufmann C, Kim M, Koch K, Bin Kwak Y, Kwon JS, Lazaro L, Li CR, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minnuzi L, Moreira PS, Morgado P, Nakagawa A, Nakamae T, Narayanaswamy JC, Nurmi EL, Ortiz AE, Pariente JC, Piacentini J, Picó-Pérez M, Piras F, Piras F, Pittenger C, Reddy YCJ, Rodriguez-Manrique D, Sakai Y, Shimizu E, Shivakumar V, Simpson HB, Soreni N, Soriano-Mas C, Sousa N, Spalletta G, Stern ER, Stevens MC, Stewart SE, Szeszko PR, Takahashi J, Tanamatis T, Tang J, Thorsen AL, Tolin D, van der Werf YD, van Marle H, van Wingen GA, Vecchio D, Venkatasubramanian G, Walitza S, Wang J, Wang Z, Watanabe A, Wolters LH, Xu X, Yun JY, Zhao Q, White T, Thompson P, Stein D, van den Heuvel O, Vriend C. The thalamus and its subnuclei—a gateway to obsessive-compulsive disorder. Translational Psychiatry 2022, 12: 70. PMID: 35190533, PMCID: PMC8861046, DOI: 10.1038/s41398-022-01823-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrainChildHumansMagnetic Resonance ImagingObsessive-Compulsive DisorderThalamusConceptsObsessive-compulsive disorderMagnetic resonance imagingThalamic volumeOCD patientsThalamic subregionsT1-weighted brain magnetic resonance imagingBrain magnetic resonance imagingClinical-level symptomsLarger thalamic volumesPediatric OCD patientsAdult OCD patientsSeparate multiple linear regression modelsVolumetric group differencesThalamus sizeMedicated patientsAdolescent patientsAnterior thalamusHealthy controlsSubregional volumesGeneral populationMedication statusMultiple comparison correctionPatientsResonance imagingIntracranial volume
2021
Characterizing neuroanatomic heterogeneity in people with and without ADHD based on subcortical brain volumes
Li T, van Rooij D, Mota N, Buitelaar J, Ambrosino S, Banaschewski T, Bandeira C, Bau C, Baumeister S, Baur‐Streubel R, Bellgrove M, Biederman J, Bralten J, Bramati I, Brandeis D, Berm S, Busatto G, Calvo A, Castellanos F, Cercignani M, Chantiluke K, Christakou A, Coghill D, Conzelmann A, Cubillo A, Cupertino R, de Zeeuw P, Durston S, Earl E, Epstein J, Ethofer T, Fallgatter A, Fair D, Faraone S, Frodl T, Gabel M, Gogberashvili T, Grevet E, Haavik J, Harrison N, Hartman C, Heslenfeld D, Hoekstra P, Høvik M, Jahanshad N, Kardatzki B, Karkashadze G, Kelly C, Kohls G, Konrad K, Kuntsi J, Lazaro L, Lera‐Miguel S, Lesch K, Louza M, Lundervold A, Malpas C, Mattos P, McCarthy H, Nicolau R, Nigg J, Tuura R, Oosterlaan J, Oranje B, Paloyelis Y, Pauli P, Picon F, Plessen K, Ramos‐Quiroga J, Reif A, Reneman L, Rosa P, Rubia K, Schrantee A, Schweren L, Seitz J, Shaw P, Silk T, Skokauskas N, Vila J, Soloveva A, Stevens M, Sudre G, Tamm L, Thompson P, Tovar‐Moll F, van Erp T, Vance A, Vilarroya O, Vives‐Gilabert Y, von Polier G, Walitza S, Yoncheva Y, Zanetti M, Ziegler G, Anikin A, Asherson P, Baranov A, Chaim‐Avanicini T, Dale A, Doyle A, Jernigan T, Hohmann S, Kapilushniy D, Mehta M, Namazova‐Baranova L, Novotny S, Weiss E, Schwarz L, Hoogman M, Vasquez A, Franke B. Characterizing neuroanatomic heterogeneity in people with and without ADHD based on subcortical brain volumes. Journal Of Child Psychology And Psychiatry 2021, 62: 1140-1149. PMID: 33786843, PMCID: PMC8403135, DOI: 10.1111/jcpp.13384.Peer-Reviewed Original ResearchAdultAttention Deficit Disorder with HyperactivityBrainCase-Control StudiesFemaleHumansMagnetic Resonance ImagingMaleThalamus
2019
Brain Imaging of the Cortex in ADHD: A Coordinated Analysis of Large-Scale Clinical and Population-Based Samples
Hoogman M, Muetzel R, Guimaraes J, Shumskaya E, Mennes M, Zwiers M, Jahanshad N, Sudre G, Wolfers T, Earl E, Soliva Vila J, Vives-Gilabert Y, Khadka S, Novotny S, Hartman C, Heslenfeld D, Schweren L, Ambrosino S, Oranje B, de Zeeuw P, Chaim-Avancini T, Rosa P, Zanetti M, Malpas C, Kohls G, von Polier G, Seitz J, Biederman J, Doyle A, Dale A, van Erp T, Epstein J, Jernigan T, Baur-Streubel R, Ziegler G, Zierhut K, Schrantee A, Høvik M, Lundervold A, Kelly C, McCarthy H, Skokauskas N, O’Gorman Tuura R, Calvo A, Lera-Miguel S, Nicolau R, Chantiluke K, Christakou A, Vance A, Cercignani M, Gabel M, Asherson P, Baumeister S, Brandeis D, Hohmann S, Bramati I, Tovar-Moll F, Fallgatter A, Kardatzki B, Schwarz L, Anikin A, Baranov A, Gogberashvili T, Kapilushniy D, Solovieva A, El Marroun H, White T, Karkashadze G, Namazova-Baranova L, Ethofer T, Mattos P, Banaschewski T, Coghill D, Plessen K, Kuntsi J, Mehta M, Paloyelis Y, Harrison N, Bellgrove M, Silk T, Cubillo A, Rubia K, Lazaro L, Brem S, Walitza S, Frodl T, Zentis M, Castellanos F, Yoncheva Y, Haavik J, Reneman L, Conzelmann A, Lesch K, Pauli P, Reif A, Tamm L, Konrad K, Oberwelland Weiss E, Busatto G, Louza M, Durston S, Hoekstra P, Oosterlaan J, Stevens M, Ramos-Quiroga J, Vilarroya O, Fair D, Nigg J, Thompson P, Buitelaar J, Faraone S, Shaw P, Tiemeier H, Bralten J, Franke B. Brain Imaging of the Cortex in ADHD: A Coordinated Analysis of Large-Scale Clinical and Population-Based Samples. American Journal Of Psychiatry 2019, 176: 531-542. PMID: 31014101, PMCID: PMC6879185, DOI: 10.1176/appi.ajp.2019.18091033.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderCortical measuresDeficit hyperactivity disorderChild Behavior ChecklistAdult groupAttention ScaleADHD symptomsAttention problemsCortical thicknessFusiform gyrusHyperactivity disorderADHD diagnosisCortical surface areaLifespan trajectoriesBehavior ChecklistFamilial effectsFuture longitudinal studiesTemporal regionsNeuroimage studiesBrain regionsLarge significant effectLow surface area valuesLongitudinal studyAdolescentsFrontal cortex
2017
Altered Functional Connectivity in Sickle Cell Disease Exists at Rest and During Acute Pain Challenge
Zempsky W, Stevens M, Santanelli J, Gaynor A, Khadka S. Altered Functional Connectivity in Sickle Cell Disease Exists at Rest and During Acute Pain Challenge. The Clinical Journal Of Pain 2017, 33: 1060-1070. PMID: 28272117, DOI: 10.1097/ajp.0000000000000492.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgingAnemia, Sickle CellBrainBrain MappingFemaleHumansMagnetic Resonance ImagingMaleNeural PathwaysPainPhysical StimulationRestYoung AdultConceptsSickle cell diseaseChronic pain disordersPain challengePain disordersCell diseaseSomatosensory networkBrain regionsAltered functional connectivityFunctional connectivity abnormalitiesSubcortical brain regionsLower functional integrationDefault mode networkCentral sensitizationRed blood cellsNociceptive informationPain sensitizationChronic painPain responseParietal lobe regionsPressure algometerPainful stimuliNeurodevelopmental abnormalitiesSCD controlsConnectivity abnormalitiesSalience network
2016
Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis
Boedhoe PS, Schmaal L, Abe Y, Ameis SH, Arnold PD, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Bose A, Brem S, Calvo A, Cheng Y, Cho KI, Dallaspezia S, Denys D, Fitzgerald KD, Fouche JP, Giménez M, Gruner P, Hanna GL, Hibar DP, Hoexter MQ, Hu H, Huyser C, Ikari K, Jahanshad N, Kathmann N, Kaufmann C, Koch K, Kwon JS, Lazaro L, Liu Y, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minuzzi L, Nakamae T, Nakao T, Narayanaswamy JC, Piras F, Piras F, Pittenger C, Reddy YC, Sato JR, Simpson HB, Soreni N, Soriano-Mas C, Spalletta G, Stevens MC, Szeszko PR, Tolin DF, Venkatasubramanian G, Walitza S, Wang Z, van Wingen GA, Xu J, Xu X, Yun JY, Zhao Q, Thompson P, Stein D, van den Heuvel O, Abe Y, Alonso P, Ameis S, Arnold P, Bargalló N, Batistuzzo M, Benedetti F, Beucke J, Boedhoe P, Bollettini I, Bose A, Brem S, Busatto G, Calvo A, Calvo R, Cath D, Cheng Y, Cho K, Dallaspezia S, de Vries F, de Wit S, Denys D, Fang Y, Fitzgerald K, Fontaine M, Fouche J, Giménez M, Gruner P, Hanna G, Hibar D, Hoexter M, Hu H, Huyser C, Ikari K, Jahanshad N, Kathmann N, Kaufmann C, Khadka S, Koch K, Kwon J, Lazaro L, Liu Y, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón J, Miguel E, Minuzzii L, Morer A, Nakamae T, Nakao T, Narayanaswamy J, Piras F, Piras F, Pittenger C, Reddy Y, Sato J, Simpson H, Schmaal L, Soreni N, Soriano-Mas C, Spalletta G, Stein D, Stevens M, Szeszko P, Thompson P, Tolin D, Veltman D, Venkatasubramanian G, van den Heuvel O, van der Werf Y, van Wingen G, Walitza S, Wang Z, Xu J, Xu X, Yun J, Zhao Q. Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis. American Journal Of Psychiatry 2016, 174: 60-69. PMID: 27609241, PMCID: PMC5344782, DOI: 10.1176/appi.ajp.2016.16020201.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildGlobus PallidusHippocampusHumansMagnetic Resonance ImagingMiddle AgedNeuroimagingObsessive-Compulsive DisorderOrgan SizeThalamusYoung AdultConceptsAdult obsessive-compulsive disorderObsessive-compulsive disorderOCD patientsLarger thalamic volumesSubcortical volume alterationsSmaller hippocampal volumesAdult OCD patientsPediatric obsessive-compulsive disorderPotential modulating effectSubcortical brain volumesLimited statistical powerPallidum volumeClinical characteristicsAdult patientsPediatric patientsMean ageThalamic volumeControl subjectsPediatric controlsSubcortical abnormalitiesIllness profileHippocampal volumeHealthy subjectsNeurodevelopmental alterationsPatientsNeurofunctional Reward Processing Changes in Cocaine Dependence During Recovery
Balodis IM, Kober H, Worhunsky PD, Stevens MC, Pearlson GD, Carroll KM, Potenza MN. Neurofunctional Reward Processing Changes in Cocaine Dependence During Recovery. Neuropsychopharmacology 2016, 41: 2112-2121. PMID: 26792441, PMCID: PMC4908642, DOI: 10.1038/npp.2016.11.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnticipation, PsychologicalBrainBrain MappingCocaine-Related DisordersFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRewardConceptsLeft inferior frontal gyrus activityCD participantsNegative urine screensReward/loss processingHealthy control participantsReward processingMeaningful outcome indicatorsDopamine-innervated regionsFunctional magnetic resonanceInferior frontal gyrus activityCD outpatientsTest-retest resultsPrefrontal cortex activityVentromedial prefrontal cortex activityUrine screensNeurofunctional alterationsVentral striatal activityCD groupNeurofunctional changesLong-term recoveryDrug useNeurobiological changesCocaine abstinenceCocaine dependenceStriatal activity
2015
Language comprehension and brain function in individuals with an optimal outcome from autism
Eigsti IM, Stevens MC, Schultz RT, Barton M, Kelley E, Naigles L, Orinstein A, Troyb E, Fein DA. Language comprehension and brain function in individuals with an optimal outcome from autism. NeuroImage Clinical 2015, 10: 182-191. PMID: 26862477, PMCID: PMC4707189, DOI: 10.1016/j.nicl.2015.11.014.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAutism Spectrum DisorderBrainBrain MappingChildComprehensionFemaleHumansLanguageMagnetic Resonance ImagingMaleNeural PathwaysYoung AdultConceptsAutism spectrum disorderTypical developmentTD groupBrain networksSentence comprehension taskIndividuals ages 8Functional MRI scansLanguage comprehensionASD groupComprehension taskLanguage abilityLateralized regionsLanguage performanceRight homologueOO individualsSpectrum disorderBrain functioningPosterior cingulateLanguage processingAge 8Temporal regionsBrain regionsBrain functionMinority of individualsIntensive learningA Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers
Worhunsky PD, Dager AD, Meda SA, Khadka S, Stevens MC, Austad CS, Raskin SA, Tennen H, Wood RM, Fallahi CR, Potenza MN, Pearlson GD. A Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers. Neuropsychopharmacology 2015, 41: 1637-1647. PMID: 26514582, PMCID: PMC4832027, DOI: 10.1038/npp.2015.332.Peer-Reviewed Original ResearchConceptsAlcohol useYoung adult drinkersYoung adultsPreliminary prospective studyAdult drinkersExcessive alcohol useAlcohol use disorderFunctional network activityProspective studyUse disordersFunctional brain networksGo/No-Go taskNeurobiological alterationsDomain scoresGreater riskDaily drinksAddictive disordersDrinkersDrinking occasionsLongitudinal studyFronto-parietal circuitryBrain networksStereotaxic Magnetic Resonance Imaging Brain Atlases for Infants from 3 to 12 Months
Fillmore P, Richards J, Phillips-Meek M, Cryer A, Stevens M. Stereotaxic Magnetic Resonance Imaging Brain Atlases for Infants from 3 to 12 Months. Developmental Neuroscience 2015, 37: 515-532. PMID: 26440296, PMCID: PMC4644510, DOI: 10.1159/000438749.Peer-Reviewed Original ResearchMeSH KeywordsAnatomy, ArtisticAtlases as TopicBrainBrain MappingFemaleHumansImage Processing, Computer-AssistedInfantMagnetic Resonance ImagingMaleConceptsMagnetic resonance imagingAdult brainBrain structuresInfant brainAge-appropriate templatesFirst yearIndividual brain regionsSubcortical areasCortical areasBrain areasInfant ageResonance imagingBrain regionsInfant developmentInfantsMRI templateBrainStereotaxic atlasStereotaxic atlasesAgeInfant participantsBrain atlasesCurrent studyIndividualsParticipantsA preliminary study of the effects of working memory training on brain function
Stevens MC, Gaynor A, Bessette KL, Pearlson GD. A preliminary study of the effects of working memory training on brain function. Brain Imaging And Behavior 2015, 10: 387-407. PMID: 26138580, PMCID: PMC4698365, DOI: 10.1007/s11682-015-9416-2.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderWM trainingMemory trainingBrain regionsDifferent neural correlatesBrain functionADHD symptom severityTraining-related changesTemporal lobe regionsDifferent symptom typesWM abilityExecutive processingWM performanceFMRI taskFrontoparietal circuitsNeural correlatesBrain activationHyperactivity disorderNeuropsychological testsNeural changesBrain activityTask phasesLobe regionsActivation gainControl participants
2014
Evaluating Methods for Constructing Average High-Density Electrode Positions
Richards J, Boswell C, Stevens M, Vendemia J. Evaluating Methods for Constructing Average High-Density Electrode Positions. Brain Topography 2014, 28: 70-86. PMID: 25234713, PMCID: PMC4293342, DOI: 10.1007/s10548-014-0400-8.Peer-Reviewed Original Research
2013
Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition
Tolin DF, Witt ST, Stevens MC. Hoarding disorder and obsessive–compulsive disorder show different patterns of neural activity during response inhibition. Psychiatry Research 2013, 221: 142-148. PMID: 24389161, PMCID: PMC3946244, DOI: 10.1016/j.pscychresns.2013.11.009.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderGo/NoGo taskFunctional magnetic resonance imagingOCD patientsHD patientsResponse inhibitionNoGo taskHealthy controlsGo/NoGo task performanceDistinct neural underpinningsRight orbitofrontal gyrusErrors of commissionNeural underpinningsOrbitofrontal activationTask performanceCorrect rejectsMagnetic resonance imagingHemodynamic activityFrontal hypoactivityNeural activityOrbitofrontal gyrusBehavioral dataHemodynamic responsePatientsPreliminary evidenceA pilot study linking reduced fronto–Striatal recruitment during reward processing to persistent bingeing following treatment for binge‐eating disorder
Balodis IM, Grilo CM, Kober H, Worhunsky PD, White MA, Stevens MC, Pearlson GD, Potenza MN. A pilot study linking reduced fronto–Striatal recruitment during reward processing to persistent bingeing following treatment for binge‐eating disorder. International Journal Of Eating Disorders 2013, 47: 376-384. PMID: 24729034, PMCID: PMC3986812, DOI: 10.1002/eat.22204.Peer-Reviewed Original ResearchMeSH KeywordsAdultBinge-Eating DisorderBody Mass IndexBrain MappingCorpus StriatumFemaleFrontal LobeHumansMagnetic Resonance ImagingMaleMiddle AgedMotivationObesityPilot ProjectsRewardConceptsBinge-eating disorderFunctional magnetic resonance imagingReward processingMonetary incentive delay taskInferior frontal gyrusIncentive delay taskBinge-eating statusMedial prefrontal cortexBrain reward circuitryNeural correlatesDelay taskSpecific brain regionsFrontal gyrusNeurobiological underpinningsOutcome phasePrefrontal cortexReward circuitryVentral striatumAnticipatory phaseBrain regionsTreatment outcomesDiminished recruitmentProcessingMagnetic resonance imagingIndividualsProlonged hemodynamic response during incidental facial emotion processing in inter-episode bipolar I disorder
Rosenfeld ES, Pearlson GD, Sweeney JA, Tamminga CA, Keshavan MS, Nonterah C, Stevens MC. Prolonged hemodynamic response during incidental facial emotion processing in inter-episode bipolar I disorder. Brain Imaging And Behavior 2013, 8: 73-86. PMID: 23975275, PMCID: PMC3944373, DOI: 10.1007/s11682-013-9246-z.Peer-Reviewed Original ResearchConceptsFMRI studyDorsolateral prefrontal cortex responsesAutomatic emotion regulationAffectively salient stimuliFacial emotion processingGender discrimination taskBrain regionsRemitted bipolar disorderPrefrontal cortex responsesResidual mood symptomsPrefrontal cortex regionsDiagnostic group differencesVentromedial prefrontal cortex regionsCortex brain regionsAngry expressionsEmotion regulationEmotion processingEmotional processingBrain activationTask performanceHemodynamic responseEmotional reactionsBipolar disorderBipolar IPrefrontal cortexError processing in current and former cocaine users
Castelluccio BC, Meda SA, Muska CE, Stevens MC, Pearlson GD. Error processing in current and former cocaine users. Brain Imaging And Behavior 2013, 8: 87-96. PMID: 23949893, PMCID: PMC3925762, DOI: 10.1007/s11682-013-9247-y.Peer-Reviewed Original ResearchConceptsFormer cocaine usersError processingSupramarginal gyrusCocaine usersBOLD responseRight inferior parietal lobuleAspects of impulsivityAbstinent cocaine usersCocaine abuse/dependenceInferior parietal lobuleCocaine-dependent individualsCurrent cocaine usersCognitive compensationNeural differencesPrepotent responsesResponse inhibitionAbuse/dependenceCorrect rejectionsSpecific deficitsBOLD activityTrait measuresMaladaptive behaviorsParietal lobuleAddictive behaviorsNeural activityfMRI response during figural memory task performance in college drinkers
Dager AD, Jamadar S, Stevens MC, Rosen R, Jiantonio-Kelly RE, Sisante JF, Raskin SA, Tennen H, Austad CS, Wood RM, Fallahi CR, Pearlson GD. fMRI response during figural memory task performance in college drinkers. Psychopharmacology 2013, 231: 167-179. PMID: 23949205, PMCID: PMC3877735, DOI: 10.1007/s00213-013-3219-1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAlcohol DrinkingAlcoholismBrain MappingData Interpretation, StatisticalFemaleFrontal LobeHippocampusHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMemoryOxygenParietal LobePsychomotor PerformanceReaction TimeRecognition, PsychologyVisual PerceptionYoung AdultConceptsFunctional magnetic resonance imagingAlcohol use disorderBOLD responseBilateral posterior parietal cortexMemory task performanceHeavy-drinking college studentsInferior frontal activationRight dorsolateral prefrontalCorrect encodingWorse memory performanceDefault mode regionsIncorrect encodingAlcohol-related impairmentMemory-related areasHeavy drinkersGreater BOLD responseLight drinkersPosterior parietal cortexBlood oxygen level-dependent functional magnetic resonance imagingQuantity/frequencyLevel-dependent functional magnetic resonance imagingInsula responseNeural correlatesFigural memoryFrontal activationRobust Changes in Reward Circuitry During Reward Loss in Current and Former Cocaine Users During Performance of a Monetary Incentive Delay Task
Patel KT, Stevens MC, Meda SA, Muska C, Thomas AD, Potenza MN, Pearlson GD. Robust Changes in Reward Circuitry During Reward Loss in Current and Former Cocaine Users During Performance of a Monetary Incentive Delay Task. Biological Psychiatry 2013, 74: 529-537. PMID: 23778289, PMCID: PMC3775945, DOI: 10.1016/j.biopsych.2013.04.029.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnticipation, PsychologicalBrainBrain MappingCocaine-Related DisordersFemaleHumansImpulsive BehaviorMagnetic Resonance ImagingMaleRewardConceptsMonetary incentive delay taskVentral tegmental areaHealthy subjectsFormer cocaine usersLoss anticipationIncentive delay taskCocaine usersTegmental areaLoss outcomesCurrent cocaine usersDrug useAbnormal brain activation patternsCocaine addictionCurrent usersActivation patternsCocaine-using groupDelay taskLong-term cocaine abstinenceFunctional magnetic resonanceSubstance-induced alterationsBrain activation patternsCircuit abnormalitiesAnterior cingulate activationControl subjectsRisk factors