2005
Low-dose estradiol alters brain activity
Stevens MC, Clark VP, Prestwood KM. Low-dose estradiol alters brain activity. Psychiatry Research 2005, 139: 199-217. PMID: 16084069, DOI: 10.1016/j.pscychresns.2005.04.004.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingSustained attention taskAttention taskEvent-related functional magnetic resonance imagingThree-stimulus oddball taskTasks of learningAlters brain activityEstrogen replacement therapyCortical brain regionsOddball taskBehavioral performanceBrain activityPrefrontal cortexHemodynamic activityAnterior cingulateDose estrogen replacement therapyNeural activityParietal lobeBrain regionsBrain functionReplacement therapyTaskGroup participantsDouble-blind studyMotor cortex
2004
The Effect of Short‐Term Estradiol Therapy on Cognitive Function in Older Men Receiving Hormonal Suppression Therapy for Prostate Cancer
Taxel P, Stevens MC, Trahiotis M, Zimmerman J, Kaplan RF. The Effect of Short‐Term Estradiol Therapy on Cognitive Function in Older Men Receiving Hormonal Suppression Therapy for Prostate Cancer. Journal Of The American Geriatrics Society 2004, 52: 269-273. PMID: 14728639, DOI: 10.1111/j.1532-5415.2004.52067.x.Peer-Reviewed Original ResearchConceptsProstate cancerOlder menCognitive functionShort-term estradiol therapyGeneral Clinical Research CenterCognitive deficitsSex hormone-binding globulinE replacement therapyHormonal suppression therapyClinical Research CenterCommunity-dwelling menSelf-reported cognitive deficitsHormone-binding globulinEffects of estrogenSymptoms of depressionSignificant differencesStandardized neurocognitive testsEstradiol therapyHypogonadal menPostmenopausal womenSuppression therapyReplacement therapyBone turnoverHormone levelsDepressive symptoms