Low-dose estradiol alters brain activity
Stevens MC, Clark VP, Prestwood KM. Low-dose estradiol alters brain activity. Psychiatry Research 2005, 139: 199-217. PMID: 16084069, DOI: 10.1016/j.pscychresns.2005.04.004.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAttentionBrainCerebrovascular CirculationDose-Response Relationship, DrugEstradiolEstrogen Replacement TherapyFemaleHemodynamicsHumansLearningMagnetic Resonance ImagingMemoryPostmenopauseConceptsFunctional magnetic resonance imagingSustained attention taskAttention taskEvent-related functional magnetic resonance imagingThree-stimulus oddball taskTasks of learningAlters brain activityEstrogen replacement therapyCortical brain regionsOddball taskBehavioral performanceBrain activityPrefrontal cortexHemodynamic activityAnterior cingulateDose estrogen replacement therapyNeural activityParietal lobeBrain regionsBrain functionReplacement therapyTaskGroup participantsDouble-blind studyMotor cortex