2015
A Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers
Worhunsky PD, Dager AD, Meda SA, Khadka S, Stevens MC, Austad CS, Raskin SA, Tennen H, Wood RM, Fallahi CR, Potenza MN, Pearlson GD. A Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers. Neuropsychopharmacology 2015, 41: 1637-1647. PMID: 26514582, PMCID: PMC4832027, DOI: 10.1038/npp.2015.332.Peer-Reviewed Original ResearchConceptsAlcohol useYoung adult drinkersYoung adultsPreliminary prospective studyAdult drinkersExcessive alcohol useAlcohol use disorderFunctional network activityProspective studyUse disordersFunctional brain networksGo/No-Go taskNeurobiological alterationsDomain scoresGreater riskDaily drinksAddictive disordersDrinkersDrinking occasionsLongitudinal studyFronto-parietal circuitryBrain networks
2013
fMRI response during figural memory task performance in college drinkers
Dager AD, Jamadar S, Stevens MC, Rosen R, Jiantonio-Kelly RE, Sisante JF, Raskin SA, Tennen H, Austad CS, Wood RM, Fallahi CR, Pearlson GD. fMRI response during figural memory task performance in college drinkers. Psychopharmacology 2013, 231: 167-179. PMID: 23949205, PMCID: PMC3877735, DOI: 10.1007/s00213-013-3219-1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAlcohol DrinkingAlcoholismBrain MappingData Interpretation, StatisticalFemaleFrontal LobeHippocampusHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMemoryOxygenParietal LobePsychomotor PerformanceReaction TimeRecognition, PsychologyVisual PerceptionYoung AdultConceptsFunctional magnetic resonance imagingAlcohol use disorderBOLD responseBilateral posterior parietal cortexMemory task performanceHeavy-drinking college studentsInferior frontal activationRight dorsolateral prefrontalCorrect encodingWorse memory performanceDefault mode regionsIncorrect encodingAlcohol-related impairmentMemory-related areasHeavy drinkersGreater BOLD responseLight drinkersPosterior parietal cortexBlood oxygen level-dependent functional magnetic resonance imagingQuantity/frequencyLevel-dependent functional magnetic resonance imagingInsula responseNeural correlatesFigural memoryFrontal activationInfluence of Alcohol Use on Neural Response to Go/No-Go Task in College Drinkers
Ahmadi A, Pearlson GD, Meda SA, Dager A, Potenza MN, Rosen R, Austad CS, Raskin SA, Fallahi CR, Tennen H, Wood RM, Stevens MC. Influence of Alcohol Use on Neural Response to Go/No-Go Task in College Drinkers. Neuropsychopharmacology 2013, 38: 2197-2208. PMID: 23670589, PMCID: PMC3773670, DOI: 10.1038/npp.2013.119.Peer-Reviewed Original ResearchConceptsSupplementary motor areaHeavy drinkersLight drinkersCollege-age drinkersAlcohol useResponse inhibitionBlood oxygen level-dependent (BOLD) responseHeavy alcohol drinkersImportant risk factorBilateral middle frontal gyrusAlcohol use disorderBrain activityAnterior cingulate cortexGreater BOLD responseLevel-dependent responsesMiddle frontal gyrusSuperior temporal gyrusImpaired response inhibitionAlcohol drinkersRisk factorsResponse inhibition taskRight hippocampusMotor areaWarrants additional investigationBilateral parietal lobules
2012
Influence of Alcohol Use and Family History of Alcoholism on Neural Response to Alcohol Cues in College Drinkers
Dager AD, Anderson BM, Stevens MC, Pulido C, Rosen R, Jiantonio‐Kelly R, Sisante J, Raskin SA, Tennen H, Austad CS, Wood RM, Fallahi CR, Pearlson GD. Influence of Alcohol Use and Family History of Alcoholism on Neural Response to Alcohol Cues in College Drinkers. Alcohol Clinical And Experimental Research 2012, 37: e161-e171. PMID: 23078363, PMCID: PMC3548054, DOI: 10.1111/j.1530-0277.2012.01879.x.Peer-Reviewed Original ResearchConceptsAlcohol cue reactivityFamily historyHeavy drinkersCue reactivityLight drinkersHeavy drinkingMagnetic resonance imaging responseBOLD responseBlood oxygen level-dependent (BOLD) contrastAlcohol cuesVisual association regionsAlcohol use disorderAlcohol imagesFunctional magnetic resonance imaging (fMRI) responsesMedial frontal cortexGreater BOLD responseLevel-dependent contrastTemporo-parietal regionsRisk factorsFrontal cortexDorsal striatumUse disordersAnterior cingulateBeverage imagesImaging response
2010
Functional Imaging of Cognitive Control During Acute Alcohol Intoxication
Anderson BM, Stevens MC, Meda SA, Jordan K, Calhoun VD, Pearlson GD. Functional Imaging of Cognitive Control During Acute Alcohol Intoxication. Alcohol Clinical And Experimental Research 2010, 35: 156-165. PMID: 20958334, PMCID: PMC3005103, DOI: 10.1111/j.1530-0277.2010.01332.x.Peer-Reviewed Original ResearchConceptsCognitive controlError processingBrain regionsAnterior cingulateFunctional magnetic resonance imaging (fMRI) taskFunctional MRILateral prefrontal cortexParietal brain regionsFalse alarm responsesBrain hemodynamic activityFalse alarm errorsParietal lobe regionsNeural basisBehavioral performancePrefrontal cortexFMRI analysisHemodynamic activityLobe regionsAcute alcohol intoxicationAlarm errorsAlcohol effectsReaction timeAlcohol intoxicationCingulateAlarm responseBehavioral and Biological Indicators of Impulsivity in the Development of Alcohol Use, Problems, and Disorders
Lejuez CW, Magidson JF, Mitchell SH, Sinha R, Stevens MC, De Wit H. Behavioral and Biological Indicators of Impulsivity in the Development of Alcohol Use, Problems, and Disorders. Alcohol Clinical And Experimental Research 2010, 34: 1334-1345. PMID: 20491733, PMCID: PMC3182265, DOI: 10.1111/j.1530-0277.2010.01217.x.Peer-Reviewed Original Research