2022
Structural language impairment in Autism Spectrum Disorder versus Loss of Autism Diagnosis: Behavioral and neural characteristics
Larson C, Rivera-Figueroa K, Thomas H, Fein D, Stevens M, Eigsti I. Structural language impairment in Autism Spectrum Disorder versus Loss of Autism Diagnosis: Behavioral and neural characteristics. NeuroImage Clinical 2022, 34: 103043. PMID: 35567947, PMCID: PMC9112023, DOI: 10.1016/j.nicl.2022.103043.Peer-Reviewed Original ResearchMeSH KeywordsAutism Spectrum DisorderAutistic DisorderBrainHumansLanguageLanguage Development DisordersMagnetic Resonance ImagingConceptsStructural language impairmentAutism spectrum disorderLanguage impairmentSpectrum disorderAutism diagnosisLanguage-related brain regionsStructural language abilitiesStructural language difficultiesLeft hemisphere lateralizationFunctional MRI resultsFunctional neuroimaging methodsRecalling SentencesHemisphere lateralizationLanguage abilityNeural specializationADHD symptomsSocial abilitiesASD symptomsLanguage difficultiesLanguage functionNeural characteristicsNeuroimaging methodsGroup differencesBrain regionsOmnibus measure
2020
Subcortical Brain Volume, Regional Cortical Thickness, and Cortical Surface Area Across Disorders: Findings From the ENIGMA ADHD, ASD, and OCD Working Groups
Boedhoe PSW, van Rooij D, Hoogman M, Twisk JWR, Schmaal L, Abe Y, Alonso P, Ameis SH, Anikin A, Anticevic A, Arango C, Arnold PD, Asherson P, Assogna F, Auzias G, Banaschewski T, Baranov A, Batistuzzo MC, Baumeister S, Baur-Streubel R, Behrmann M, Bellgrove MA, Benedetti F, Beucke JC, Biederman J, Bollettini I, Bose A, Bralten J, Bramati IE, Brandeis D, Brem S, Brennan BP, Busatto GF, Calderoni S, Calvo A, Calvo R, Castellanos FX, Cercignani M, Chaim-Avancini TM, Chantiluke KC, Cheng Y, Cho KIK, Christakou A, Coghill D, Conzelmann A, Cubillo AI, Dale AM, Dallaspezia S, Daly E, Denys D, Deruelle C, Di Martino A, Dinstein I, Doyle AE, Durston S, Earl EA, Ecker C, Ehrlich S, Ely BA, Epstein JN, Ethofer T, Fair DA, Fallgatter AJ, Faraone SV, Fedor J, Feng X, Feusner JD, Fitzgerald J, Fitzgerald KD, Fouche JP, Freitag CM, Fridgeirsson EA, Frodl T, Gabel MC, Gallagher L, Gogberashvili T, Gori I, Gruner P, Gürsel DA, Haar S, Haavik J, Hall GB, Harrison NA, Hartman CA, Heslenfeld DJ, Hirano Y, Hoekstra PJ, Hoexter MQ, Hohmann S, Høvik MF, Hu H, Huyser C, Jahanshad N, Jalbrzikowski M, James A, Janssen J, Jaspers-Fayer F, Jernigan TL, Kapilushniy D, Kardatzki B, Karkashadze G, Kathmann N, Kaufmann C, Kelly C, Khadka S, King JA, Koch K, Kohls G, Konrad K, Kuno M, Kuntsi J, Kvale G, Kwon JS, Lázaro L, Lera-Miguel S, Lesch KP, Hoekstra L, Liu Y, Lochner C, Louza MR, Luna B, Lundervold AJ, Malpas CB, Marques P, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Mattos P, McCarthy H, McGrath J, Mehta MA, Menchón JM, Mennes M, Martinho MM, Moreira PS, Morer A, Morgado P, Muratori F, Murphy CM, Murphy DGM, Nakagawa A, Nakamae T, Nakao T, Namazova-Baranova L, Narayanaswamy JC, Nicolau R, Nigg JT, Novotny SE, Nurmi EL, Weiss EO, O'Gorman Tuura RL, O'Hearn K, O'Neill J, Oosterlaan J, Oranje B, Paloyelis Y, Parellada M, Pauli P, Perriello C, Piacentini J, Piras F, Piras F, Plessen KJ, Puig O, Ramos-Quiroga JA, Reddy YCJ, Reif A, Reneman L, Retico A, Rosa PGP, Rubia K, Rus OG, Sakai Y, Schrantee A, Schwarz L, Schweren LJS, Seitz J, Shaw P, Shook D, Silk TJ, Simpson HB, Skokauskas N, Soliva Vila JC, Solovieva A, Soreni N, Soriano-Mas C, Spalletta G, Stern ER, Stevens MC, Stewart SE, Sudre G, Szeszko PR, Tamm L, Taylor MJ, Tolin DF, Tosetti M, Tovar-Moll F, Tsuchiyagaito A, van Erp TGM, van Wingen GA, Vance A, Venkatasubramanian G, Vilarroya O, Vives-Gilabert Y, von Polier GG, Walitza S, Wallace GL, Wang Z, Wolfers T, Yoncheva YN, Yun JY, Zanetti MV, Zhou F, Ziegler GC, Zierhut KC, Zwiers MP, Thompson P, Stein D, Buitelaar J, Franke B, van den Heuvel O. Subcortical Brain Volume, Regional Cortical Thickness, and Cortical Surface Area Across Disorders: Findings From the ENIGMA ADHD, ASD, and OCD Working Groups. American Journal Of Psychiatry 2020, 177: 834-843. PMID: 32539527, PMCID: PMC8296070, DOI: 10.1176/appi.ajp.2020.19030331.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderAutism spectrum disorderObsessive-compulsive disorderDeficit hyperactivity disorderFrontal cortexCommon neurodevelopmental disorderStandardized processing protocolsStructural brain differencesCortical thickness differencesWhole-brain MRI dataCortical thicknessHyperactivity disorderCortical surface areaSpectrum disorderBrain differencesSmaller hippocampal volumesDifferent age groupsRegional cortical thicknessSubcortical brain volumesClinical groupsStructural brainSmaller intracranial volumeShared differenceNeurodevelopmental disordersHippocampal differences
2015
Restricted and Repetitive Behaviors as Predictors of Outcome in Autism Spectrum Disorders
Troyb E, Knoch K, Herlihy L, Stevens MC, Chen CM, Barton M, Treadwell K, Fein D. Restricted and Repetitive Behaviors as Predictors of Outcome in Autism Spectrum Disorders. Journal Of Autism And Developmental Disorders 2015, 46: 1282-1296. PMID: 26676629, PMCID: PMC8054273, DOI: 10.1007/s10803-015-2668-2.Peer-Reviewed Original ResearchMeSH KeywordsAutism Spectrum DisorderChildChild, PreschoolCognitionFemaleHumansInfantMalePrognosisStereotyped BehaviorConceptsAutism spectrum disorderSpectrum disorderRepetitive behaviorsGreater ASD symptom severityAge 8ASD symptom severityParts of objectsASD symptomatologyCognitive functioningAdaptive skillsSensory interestsStereotyped motor movementsPreschool yearsMotor movementsLate childhoodSymptom severityAdaptive abilityRRBsChildrenPredictors of outcomeOutcome of childrenDisordersFunctioningSkillsSymptomatologyLanguage comprehension and brain function in individuals with an optimal outcome from autism
Eigsti IM, Stevens MC, Schultz RT, Barton M, Kelley E, Naigles L, Orinstein A, Troyb E, Fein DA. Language comprehension and brain function in individuals with an optimal outcome from autism. NeuroImage Clinical 2015, 10: 182-191. PMID: 26862477, PMCID: PMC4707189, DOI: 10.1016/j.nicl.2015.11.014.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAutism Spectrum DisorderBrainBrain MappingChildComprehensionFemaleHumansLanguageMagnetic Resonance ImagingMaleNeural PathwaysYoung AdultConceptsAutism spectrum disorderTypical developmentTD groupBrain networksSentence comprehension taskIndividuals ages 8Functional MRI scansLanguage comprehensionASD groupComprehension taskLanguage abilityLateralized regionsLanguage performanceRight homologueOO individualsSpectrum disorderBrain functioningPosterior cingulateLanguage processingAge 8Temporal regionsBrain regionsBrain functionMinority of individualsIntensive learningPsychiatric Symptoms in Youth with a History of Autism and Optimal Outcome
Orinstein A, Tyson KE, Suh J, Troyb E, Helt M, Rosenthal M, Barton ML, Eigsti IM, Kelley E, Naigles L, Schultz RT, Stevens MC, Fein DA. Psychiatric Symptoms in Youth with a History of Autism and Optimal Outcome. Journal Of Autism And Developmental Disorders 2015, 45: 3703-3714. PMID: 26155764, PMCID: PMC4609588, DOI: 10.1007/s10803-015-2520-8.Peer-Reviewed Original ResearchConceptsHigh-functioning autismAutism spectrum disorderHFA groupPsychiatric disordersHistory of autismSocial phobiaSpectrum disorderSpecific phobiaParent interviewsGeneralized anxietyElevated depressionAge 8AutismDSM-IV psychiatric disordersSubthreshold symptomsOO groupPsychiatric symptomsPhobiaCurrent ADHDYouthDisordersOptimal outcomesADHDPsychopathologyAnxiety