2013
Diffusion Tensor Imaging White Matter Endophenotypes in Patients With Schizophrenia or Psychotic Bipolar Disorder and Their Relatives
Skudlarski P, Schretlen DJ, Thaker GK, Stevens MC, Keshavan MS, Sweeney JA, Tamminga CA, Clementz BA, O’Neil K, Pearlson GD. Diffusion Tensor Imaging White Matter Endophenotypes in Patients With Schizophrenia or Psychotic Bipolar Disorder and Their Relatives. American Journal Of Psychiatry 2013, 170: 886-898. PMID: 23771210, DOI: 10.1176/appi.ajp.2013.12111448.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnisotropyBipolar DisorderBrainDiffusion Tensor ImagingDominance, CerebralEndophenotypesGenetic Predisposition to DiseaseHumansImage Interpretation, Computer-AssistedLeukoencephalopathiesNerve NetPhenotypePsychiatric Status Rating ScalesReference ValuesSchizophreniaSchizophrenic PsychologyStatistics as TopicConceptsPsychotic bipolar disorderBipolar disorderWhite matter integrityFractional anisotropyComparison subjectsFractional anisotropy decreasesFirst-degree relativesHealthy comparison subjectsLower white matter integrityDiffusion tensorMultiple white matter regionsLower fractional anisotropyWhite matter regionsBipolar-Schizophrenia NetworkHealthy subjectsBipolar relativesProband groupsYoung subjectsBrain regionsDisease specificityFractional anisotropy measuresUnaffected relativesMatter regionsBrain connectivitySchizophrenia
2009
Investigation of relationships between fMRI brain networks in the spectral domain using ICA and Granger causality reveals distinct differences between schizophrenia patients and healthy controls
Demirci O, Stevens MC, Andreasen NC, Michael A, Liu J, White T, Pearlson GD, Clark VP, Calhoun VD. Investigation of relationships between fMRI brain networks in the spectral domain using ICA and Granger causality reveals distinct differences between schizophrenia patients and healthy controls. NeuroImage 2009, 46: 419-431. PMID: 19245841, PMCID: PMC2713821, DOI: 10.1016/j.neuroimage.2009.02.014.Peer-Reviewed Original ResearchConceptsFunctional network connectivitySternberg Item Recognition ParadigmTemporal lobe activationBrain networksBrain activation networksCerebral sitesHealthy controlsAuditory oddball taskPsychiatric disordersSchizophrenia patientsControl groupAOD taskCausal relationshipFMRI brain networksTime courseOddball task