2024
A randomized clinical trial to evaluate feasibility, tolerability, and preliminary target engagement for a novel executive working memory training in adolescents with ADHD
Sullivan A, Anderson J, Beatty M, Choi J, Jaccard J, Hawkins K, Pearlson G, Stevens M. A randomized clinical trial to evaluate feasibility, tolerability, and preliminary target engagement for a novel executive working memory training in adolescents with ADHD. Behaviour Research And Therapy 2024, 181: 104615. PMID: 39173523, PMCID: PMC11465636, DOI: 10.1016/j.brat.2024.104615.Peer-Reviewed Original ResearchExecutive working memoryAttention-deficit/hyperactivity disorderWorking memory trainingMemory trainingExecutive working memory taskIncreased working memory capacityMedium effect size improvementsEffect size improvementsSelf-rated motivationIntervention participantsTarget engagementTrial retentionWorking memoryAttention-deficit/hyperactivityDifficulty manipulationPlacebo-controlled studyMemory capacityTask accuracySize improvementsMemory contentIntervention tolerabilityTraining targetBehavioral changesPrimary outcome measureCoaching sessions
2009
Evidence for Anomalous Network Connectivity during Working Memory Encoding in Schizophrenia: An ICA Based Analysis
Meda SA, Stevens MC, Folley BS, Calhoun VD, Pearlson GD. Evidence for Anomalous Network Connectivity during Working Memory Encoding in Schizophrenia: An ICA Based Analysis. PLOS ONE 2009, 4: e7911. PMID: 19936244, PMCID: PMC2775682, DOI: 10.1371/journal.pone.0007911.Peer-Reviewed Original ResearchConceptsTask accuracyFunctional connectivityPrefrontal cortexNetwork engagementLeft fronto-parietal networkRight dorsolateral prefrontal cortexMemory fMRI paradigmWorking Memory EncodingFronto-parietal networkVentrolateral prefrontal cortexNumerous neuroimaging studiesDorsolateral prefrontal cortexIndependent component analysisAbnormal regional brain activityDefault mode networkBrain network integrationDysfunctional brain regionsPrevious schizophrenia studiesRegional brain activityHippocampus/parahippocampusMemory encodingFMRI taskMemory cognitionMemory performanceFMRI paradigm