A large scale (N=102) functional neuroimaging study of response inhibition in a Go/NoGo task
Steele VR, Aharoni E, Munro GE, Calhoun VD, Nyalakanti P, Stevens MC, Pearlson G, Kiehl KA. A large scale (N=102) functional neuroimaging study of response inhibition in a Go/NoGo task. Behavioural Brain Research 2013, 256: 529-536. PMID: 23756137, PMCID: PMC4437665, DOI: 10.1016/j.bbr.2013.06.001.Peer-Reviewed Original ResearchConceptsSuccessful response inhibitionGo/NoGo taskResponse inhibitionUnsuccessful response inhibitionMagnetic resonance imaging studySupplementary motor areaResonance imaging studyFunctional magnetic resonance imaging studyInferior parietal lobuleNoGo taskInferior prefrontal regionsHealthy adult participantsBasal gangliaInferior frontal gyrusHemodynamic responseMotor areaAnterior cingulateImaging studiesParietal lobuleFronto-parietal networkHemodynamic activityFrontal gyrusFrontostriatal regionsSmall sample studiesPrefrontal regionsInfluence of Alcohol Use on Neural Response to Go/No-Go Task in College Drinkers
Ahmadi A, Pearlson GD, Meda SA, Dager A, Potenza MN, Rosen R, Austad CS, Raskin SA, Fallahi CR, Tennen H, Wood RM, Stevens MC. Influence of Alcohol Use on Neural Response to Go/No-Go Task in College Drinkers. Neuropsychopharmacology 2013, 38: 2197-2208. PMID: 23670589, PMCID: PMC3773670, DOI: 10.1038/npp.2013.119.Peer-Reviewed Original ResearchConceptsSupplementary motor areaHeavy drinkersLight drinkersCollege-age drinkersAlcohol useResponse inhibitionBlood oxygen level-dependent (BOLD) responseHeavy alcohol drinkersImportant risk factorBilateral middle frontal gyrusAlcohol use disorderBrain activityAnterior cingulate cortexGreater BOLD responseLevel-dependent responsesMiddle frontal gyrusSuperior temporal gyrusImpaired response inhibitionAlcohol drinkersRisk factorsResponse inhibition taskRight hippocampusMotor areaWarrants additional investigationBilateral parietal lobules