2015
A Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers
Worhunsky PD, Dager AD, Meda SA, Khadka S, Stevens MC, Austad CS, Raskin SA, Tennen H, Wood RM, Fallahi CR, Potenza MN, Pearlson GD. A Preliminary Prospective Study of an Escalation in ‘Maximum Daily Drinks’, Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers. Neuropsychopharmacology 2015, 41: 1637-1647. PMID: 26514582, PMCID: PMC4832027, DOI: 10.1038/npp.2015.332.Peer-Reviewed Original ResearchConceptsAlcohol useYoung adult drinkersYoung adultsPreliminary prospective studyAdult drinkersExcessive alcohol useAlcohol use disorderFunctional network activityProspective studyUse disordersFunctional brain networksGo/No-Go taskNeurobiological alterationsDomain scoresGreater riskDaily drinksAddictive disordersDrinkersDrinking occasionsLongitudinal studyFronto-parietal circuitryBrain networks
2013
Functional Brain Networks Associated With Cognitive Control, Cocaine Dependence, and Treatment Outcome
Worhunsky PD, Stevens MC, Carroll KM, Rounsaville BJ, Calhoun VD, Pearlson GD, Potenza MN. Functional Brain Networks Associated With Cognitive Control, Cocaine Dependence, and Treatment Outcome. Psychology Of Addictive Behaviors 2013, 27: 477-488. PMID: 22775772, PMCID: PMC3743442, DOI: 10.1037/a0029092.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceBehavior, AddictiveCase-Control StudiesCerebral CortexCocaine-Related DisordersCognitive Behavioral TherapyData Interpretation, StatisticalExecutive FunctionFemaleFunctional NeuroimagingHumansLimbic SystemLinear ModelsMagnetic Resonance ImagingMaleMotivationNerve NetOxygenPrincipal Component AnalysisPsychomotor PerformanceStroop TestTreatment OutcomeConceptsCognitive controlCocaine dependencePoor cognitive controlCognitive control processesFunctional networksTreatment retentionDistinct functional networksIndependent component analysisFunctional brain networksConflict monitoringStroop taskTreatment outcome measuresMotivational processingCocaine-dependent patientsPrefrontal networkBrain networksSubcortical networksFunctional connectivityControl participantsFMRI dataRegional activationReduced involvementCortical networksTreatment developmentControl process