Thrombospondin Type 1 Repeats Interact with Matrix Metalloproteinase 2 REGULATION OF METALLOPROTEINASE ACTIVITY*
Bein K, Simons M. Thrombospondin Type 1 Repeats Interact with Matrix Metalloproteinase 2 REGULATION OF METALLOPROTEINASE ACTIVITY*. Journal Of Biological Chemistry 2000, 275: 32167-32173. PMID: 10900205, DOI: 10.1074/jbc.m003834200.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBinding SitesBlotting, WesternCatalytic DomainCattleCell LineCollagenasesEnzyme ActivationEnzyme PrecursorsHumansMatrix Metalloproteinase 2Matrix Metalloproteinase 3Matrix Metalloproteinase 9Matrix Metalloproteinase InhibitorsPeptide FragmentsPrecipitin TestsProperdinProtein BindingProtein Structure, TertiaryRepetitive Sequences, Amino AcidSaccharomyces cerevisiaeThrombinThrombospondin 1ThrombospondinsTwo-Hybrid System TechniquesConceptsIntact thrombospondin-1Thrombospondin-1Ability of TSP1Matrix metalloproteinase-2Two-hybrid systemType 1 repeatsCatalytic domainCDNA clonesProtein interactionsThrombospondin type 1Terminal regionGelatin-binding domainAmino acidsInhibitors of angiogenesisCatalytic centerMMP activityTSP2Western blottingProteinTissue cultureClonesMapping sitesMetalloproteinase activityActivationMetalloproteinase-2