2000
Inhibition of ubiquitin-proteasome pathway–mediated IκBα degradation by a naturally occurring antibacterial peptide
Gao Y, Lecker S, Post M, Hietaranta A, Li J, Volk R, Li M, Sato K, Saluja A, Steer M, Goldberg A, Simons M. Inhibition of ubiquitin-proteasome pathway–mediated IκBα degradation by a naturally occurring antibacterial peptide. Journal Of Clinical Investigation 2000, 106: 439-448. PMID: 10930447, PMCID: PMC314329, DOI: 10.1172/jci9826.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesCells, CulturedCysteine EndopeptidasesDNA-Binding ProteinsGene ExpressionHumansI-kappa B ProteinsMaleMiceMice, Inbred ICRMice, TransgenicMultienzyme ComplexesMyocardial InfarctionNF-kappa BNF-KappaB Inhibitor alphaPancreatitisPeptidesProteasome Endopeptidase ComplexSwineUbiquitinsConceptsDependent gene expressionGene expressionNF-kappa BUbiquitin-proteasome pathwayB alpha phosphorylationValosin-containing proteinB alpha degradationNF-kappa B inhibitor ICellular functionsTranscription factorsAlpha phosphorylationBiological processesInhibitor IAlpha 7 subunitSelective regulationProteasome activityB alphaAntibacterial peptidesOverall proteasome activityAlpha degradationNF-kappaBCell culturesIκBα degradationExpressionPeptides
1997
c‐Myb function in fibroblasts
Bein K, Husain M, Ware J, Mucenski M, Rosenberg R, Simons M. c‐Myb function in fibroblasts. Journal Of Cellular Physiology 1997, 173: 319-326. PMID: 9369944, DOI: 10.1002/(sici)1097-4652(199712)173:3<319::aid-jcp3>3.0.co;2-q.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAnimalsCalciumCell CycleCells, CulturedCytoplasmDNA-Binding ProteinsDrosophilaEmbryo, MammalianEmbryo, NonmammalianFibroblastsHeterozygoteHomeodomain ProteinsMiceMice, KnockoutProto-Oncogene ProteinsProto-Oncogene Proteins c-mybRecombinant Fusion ProteinsTrans-ActivatorsTranscription FactorsTranscription, GeneticTransfectionConceptsC-Myb proteinDominant-negative constructMyb DNA binding domainC-MybMYB family membersDNA binding domainsNegative constructsCell cycle regulationSignificant sequence homologyC-myb geneMouse embryonic fibroblastsC-Myb functionCell cycle progressionCell type expressionProtooncogene c-mybNIH 3T3 fibroblastsCell cycle arrestG1 cell cycle arrestNuclear transcription factorA-mybCycle regulationIntracellular calcium levelsB-MybTranscription factorsCDNA sequence