THE ANTI‐ANGIOGENIC ACTIVITY OF rPAI‐123 INHIBITS ANGIOGENIC VASA VASORUM AND ATHERSCLEROTIC PLAQUE GROWTH
Mulligan‐Kehoe M, Drinane M, Mollmark J, Simons M. THE ANTI‐ANGIOGENIC ACTIVITY OF rPAI‐123 INHIBITS ANGIOGENIC VASA VASORUM AND ATHERSCLEROTIC PLAQUE GROWTH. The FASEB Journal 2007, 21: a16-a17. DOI: 10.1096/fasebj.21.5.a16-d.Peer-Reviewed Original ResearchHigh-fat dietAnti-angiogenic activityVasa vasorumPlaque growthSaline treatmentPlaque areaPlaque progressionLumen areaRole of angiogenesisVasa vasorum densitySignificant anti-angiogenic activityAtherogenic micePlaque regressionHFD groupNeovascularized areaChow dietPAI-1 proteinFat dietAortic rootControl animalsVessel circumferenceVasorumVessel areaMiceReconstructed vessels