2006
Syndecan‐4 plays a key role in the phosphorylation of protein kinase B / Akt
Partovian C, Simons M. Syndecan‐4 plays a key role in the phosphorylation of protein kinase B / Akt. The FASEB Journal 2006, 20: a1080-a1080. DOI: 10.1096/fasebj.20.5.a1080-a.Peer-Reviewed Original ResearchPhosphoinositide-dependent kinase 1Syndecan-4Akt phosphorylationProtein kinase B/AktPhosphorylation of Thr308Hydrophobic motifActivation loopRaft fractionsEndothelial cellsKinase 1Akt activationPhosphorylationMammalian targetSyndecansThr308AktGrowth factorCentral roleRegulationCellsKey roleMajor roleRictorNumber of processesSer473
1998
Regulation of Syndecan-4 Phosphorylation in Vivo *
Horowitz A, Simons M. Regulation of Syndecan-4 Phosphorylation in Vivo *. Journal Of Biological Chemistry 1998, 273: 10914-10918. PMID: 9556568, DOI: 10.1074/jbc.273.18.10914.Peer-Reviewed Original ResearchConceptsCytoplasmic tailNovel PKC isozymesSyndecan-4Basic fibroblast growth factorProtein serine/threonine phosphatase type 1Serine/threonine phosphatasePKC isozymesSingle serine residuePhosphatase type 1Phosphatase inhibitor calyculinProtein kinase CNIH 3T3 fibroblastsThreonine phosphataseVivo phosphorylationEffects of bFGFSerine residuesTransmembrane proteoglycansConventional PKCFibroblast growth factorKinase CPhosphorylationPKC inhibitorPotential involvementGrowth factorIsozymes