2016
Adrenomedullin 2 activates extracellular-signal-regulated kinase in endothelial cells via a protein kinase C α-independent pathway
Guo X, Ju R, Cha C, Simons M. Adrenomedullin 2 activates extracellular-signal-regulated kinase in endothelial cells via a protein kinase C α-independent pathway. F1000Research 2016, 5: 26. DOI: 10.12688/f1000research.2420.1.Peer-Reviewed Original Research
1999
Phosphatidylinositol-4,5-bisphosphate Mediates the Interaction of Syndecan-4 with Protein Kinase C †
Horowitz A, Murakami M, Gao Y, Simons M. Phosphatidylinositol-4,5-bisphosphate Mediates the Interaction of Syndecan-4 with Protein Kinase C †. Biochemistry 1999, 38: 15871-15877. PMID: 10625452, DOI: 10.1021/bi991363i.Peer-Reviewed Original ResearchConceptsCytoplasmic tailSyndecan-4Protein kinase CalphaProtein kinase CExtracellular matrix proteinsActivation of PKCalphaGrowth factorExtracellular signalsDelta isoenzymesTransmembrane proteoglycansKinase CMatrix proteinsPhosphatidylinositolPKCalphaActivation mechanismCooperative activationBisphosphateActivationProteoglycansRecent studiesTailPICalphaSignalingAffinity
1998
Regulation of Syndecan-4 Phosphorylation in Vivo *
Horowitz A, Simons M. Regulation of Syndecan-4 Phosphorylation in Vivo *. Journal Of Biological Chemistry 1998, 273: 10914-10918. PMID: 9556568, DOI: 10.1074/jbc.273.18.10914.Peer-Reviewed Original ResearchConceptsCytoplasmic tailNovel PKC isozymesSyndecan-4Basic fibroblast growth factorProtein serine/threonine phosphatase type 1Serine/threonine phosphatasePKC isozymesSingle serine residuePhosphatase type 1Phosphatase inhibitor calyculinProtein kinase CNIH 3T3 fibroblastsThreonine phosphataseVivo phosphorylationEffects of bFGFSerine residuesTransmembrane proteoglycansConventional PKCFibroblast growth factorKinase CPhosphorylationPKC inhibitorPotential involvementGrowth factorIsozymes