1998
Copper resistant human hepatoblastoma mutant cell lines without metallothionein induction overexpress ATP7B
Schilsky M, Stockert R, Kesner A, Gorla G, Gagliardi G, Terada K, Miura N, Czaja M. Copper resistant human hepatoblastoma mutant cell lines without metallothionein induction overexpress ATP7B. Hepatology 1998, 28: 1347-1356. PMID: 9794921, DOI: 10.1002/hep.510280525.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphatasesBlotting, NorthernBlotting, WesternCadmiumCarrier ProteinsCation Transport ProteinsCeruloplasminCopperCopper-transporting ATPasesDrug ResistanceGene ExpressionGlutathioneHepatoblastomaHumansKineticsLiver NeoplasmsMetallothioneinMutagenesisProtein BiosynthesisRNA, MessengerTumor Cells, CulturedZincConceptsCell linesSubcellular distributionCopper uptakeCopper toxicityBasal expressionZinc toxicityMetallothionein messenger RNAMutant cell linesIndependent cell linesCellular resistanceATP7B proteinHuman hepatoblastoma cell lineMembrane fractionIntracellular sequestrationOrganellesMessenger RNAHepatoblastoma cell lineResistant cell linesProteinATP7BExpressionHuh7InductionGlutathione contentMT induction
1995
Secretion, Surface Localization, Turnover, and Steady State Expression of Protein Disulfide Isomerase in Rat Hepatocytes (∗)
Terada K, Manchikalapudi P, Noiva R, Jauregui H, Stockert R, Schilsky M. Secretion, Surface Localization, Turnover, and Steady State Expression of Protein Disulfide Isomerase in Rat Hepatocytes (∗). Journal Of Biological Chemistry 1995, 270: 20410-20416. PMID: 7657616, DOI: 10.1074/jbc.270.35.20410.Peer-Reviewed Original ResearchAnimalsBlotting, WesternCell FractionationCell MembraneCells, CulturedCysteineElectrophoresis, Polyacrylamide GelFluorescent Antibody TechniqueGene ExpressionImmunohistochemistryIsomerasesKineticsLiverMethionineMicrosomes, LiverMolecular WeightOligopeptidesPeptide MappingProtein Disulfide-IsomerasesProtein Sorting SignalsRatsRats, WistarSubcellular FractionsSulfur RadioisotopesTime Factors