1984
Beneficial effect of thyroxin on recovery from toxic acute renal failure
Siegel N, Gaudio K, Katz L, Reilly H, Ardito T, Hendler F, Kashgarian M. Beneficial effect of thyroxin on recovery from toxic acute renal failure. Kidney International 1984, 25: 906-911. PMID: 6471672, DOI: 10.1038/ki.1984.108.Peer-Reviewed Original ResearchConceptsToxic acute renal failureAcute renal failureNormal salineRenal failureBeneficial effectsInjected ratsOnly normal salineT4-treated ratsEffect of thyroxinNonspecific systemic effectsT4-treated animalsRenal insultHemodynamic effectsRenal functionRenal injuryControl ratsGlomerular functionUrine flowSimilar doseSystemic effectsEnhanced recoveryPrompt recoveryKidney preparationRatsFENa
1975
Minimal-lesion nephrotic syndrome with early resistance to steroid therapy
Siegel N, Gur A, Krassner L, Kashgarian M. Minimal-lesion nephrotic syndrome with early resistance to steroid therapy. The Journal Of Pediatrics 1975, 87: 377-380. PMID: 1165516, DOI: 10.1016/s0022-3476(75)80639-1.Peer-Reviewed Original ResearchConceptsMinimal lesion nephrotic syndromeNephrotic syndromeLong-term clinical courseEarly resistanceMinimal glomerular lesionsClinical courseSteroid responsivenessClinical outcomesPrompt remissionCyclophosphamide treatmentGlomerular lesionsHistopathologic lesionsPatientsRemissionCyclophosphamideSyndromeTherapyLesionsUltimate outcomeOutcomesChildrenCorticosteroidsPrednisoneRelapseSteroids
1973
CLINICOPATHOLOGICAL CORRELATIONS IN THE NEPHROTIC SYNDROME DUE TO PRIMARY RENAL DISEASE
HAYSLETT J, KASHGARIAN M, BENSCH K, SPARGO B, FREEDMAN L, EPSTEIN F. CLINICOPATHOLOGICAL CORRELATIONS IN THE NEPHROTIC SYNDROME DUE TO PRIMARY RENAL DISEASE. Medicine 1973, 52: 93-120. PMID: 4695844, DOI: 10.1097/00005792-197303000-00001.Peer-Reviewed Original ResearchAcute DiseaseAdolescentAdultAgedAutopsyAzathioprineBiopsyChildChild, PreschoolChronic DiseaseFemaleFollow-Up StudiesGlomerulonephritisHumansKidney DiseasesKidney Function TestsMaleMicroscopy, ElectronMiddle AgedNephrosis, LipoidNephrotic SyndromePrednisonePrognosisProteinuriaRemission, SpontaneousSerum AlbuminUrine
1971
Successful Treatment of Renal Failure in Goodpasture's Syndrome
Hayslett J, Berte J, Kashgarian M. Successful Treatment of Renal Failure in Goodpasture's Syndrome. JAMA Internal Medicine 1971, 127: 953-957. PMID: 5560872, DOI: 10.1001/archinte.1971.00310170161025.Peer-Reviewed Original ResearchConceptsGoodpasture's syndromeRenal failureYale-New Haven HospitalEvaluation of hemoptysisSymptoms of bronchospasmFurther renal deteriorationGlomerular basement membraneAcute bronchitisRenal deteriorationRenal insufficiencyPulmonary functionPulmonary tuberculosisSuccessful treatmentRapid progressionProlonged survivalImmune responseSerial studiesSyndromeWhite womenHemoptysisRecent evidenceBasement membraneComplete restorationWomenBronchospasm