1995
PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products
Throckmorton D, Brogden A, Min B, Rasmussen H, Kashgarian M. PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products. Kidney International 1995, 48: 111-117. PMID: 7564067, DOI: 10.1038/ki.1995.274.Peer-Reviewed Original Research
1994
The Contribution of Mesangial Cell Collagen Synthesis to the Pathogenesis of Diabetic Nephropathy1
Kashgarian M, Oshima S, Takeuchi A, Throckmorton D, Rasmussen H. The Contribution of Mesangial Cell Collagen Synthesis to the Pathogenesis of Diabetic Nephropathy1. Contributions To Nephrology 1994, 107: 132-139. PMID: 8004959, DOI: 10.1159/000422971.Peer-Reviewed Original ResearchAnimalsCells, CulturedCollagenDiabetic NephropathiesGlomerular MesangiumGlucoseHumansPlatelet-Derived Growth FactorRatsSerotonin
1993
Spatial organization of the extracellular matrix modulates the expression of PDGF-receptor subunits in mesangial cells
Marx M, Daniel T, Kashgarian M, Madri J. Spatial organization of the extracellular matrix modulates the expression of PDGF-receptor subunits in mesangial cells. Kidney International 1993, 43: 1027-1041. PMID: 8510381, DOI: 10.1038/ki.1993.145.Peer-Reviewed Original ResearchConceptsPDGF receptor subunitsMesangial cell phenotypeCell surfaceExtracellular matrixCell phenotypeExtracellular matrix environmentSpatial organizationPDGF responsivenessPDGF receptor alphaTwo-dimensional cultureMulticellular structuresThree-dimensional cultureMetabolic labelingDifferential expressionQuiescent cellsRat mesangial cell growthCell growthPDGF isoforms AASubunitsMatrix environmentCell proliferationPDGF isoformsReceptor subunitsUltrastructural analysisSurface expression