1986
Postischemic hemodynamics and recovery of renal adenosine triphosphate
Gaudio K, Stromski M, Thulin G, Ardito T, Kashgarian M, Siegel N. Postischemic hemodynamics and recovery of renal adenosine triphosphate. American Journal Of Physiology 1986, 251: f603-f609. PMID: 3490185, DOI: 10.1152/ajprenal.1986.251.4.f603.Peer-Reviewed Original ResearchConceptsRenal blood flowIschemic acute renal injuryImportant pathophysiological componentRenal ATP levelsAcute renal injuryInfusion of dopamineSaline-treated ratsPostischemic enhancementRenal adenosineRenal vasoconstrictionRenal injuryTubular functionPathophysiological componentPostischemic infusionInulin clearanceATP-MgCl2Vasoactive compoundsTubular epitheliumBlood flowPharmacological agentsPostischemic hemodynamicsTubular cellsSaline ratsEnhances recoveryRats
1983
Accelerated cellular recovery after an ischemic renal injury.
Gaudio K, Ardito T, Reilly H, Kashgarian M, Siegel N. Accelerated cellular recovery after an ischemic renal injury. American Journal Of Pathology 1983, 112: 338-46. PMID: 6604459, PMCID: PMC1916386.Peer-Reviewed Original ResearchConceptsProximal tubular pressureCellular morphologic featuresRenal ischemiaATP-MgCl2Back leakTubular integrityMorphologic featuresCellular damageIschemic cellular damageProgressive ischemic injurySevere ischemic damageIschemic renal injurySaline-treated ratsGroups of ratsEarly regenerative changesRenal injuryIschemic damageIschemic injuryIschemic alterationsNormal salineRegenerative changesSaline ratsEnhances recoverySalutary effectsHistomorphometric analysis
1982
Accelerated recovery of single nephron function by the postischemic infusion of ATP-MgCl2
Gaudio K, Taylor M, Chaudry I, Kashgarian M, Siegel N. Accelerated recovery of single nephron function by the postischemic infusion of ATP-MgCl2. Kidney International 1982, 22: 13-20. PMID: 7120752, DOI: 10.1038/ki.1982.126.Peer-Reviewed Original ResearchConceptsClearance of inulinSingle nephron functionATP-MgCl2Proximal tubular pressureNephron functionTubular pressureBeneficial effectsRenal artery ischemiaSaline-treated animalsSaline-treated ratsCourse of recoveryGroups of animalsPostischemic administrationArtery ischemiaPattern of recoveryCIN 1Postischemic infusionInitial insultInulin clearanceInitial improvementControl animalsMost epithelial cellsEnhanced recoveryWhole kidneyTubular fluid