1987
Parathyroid hormone directly inhibits tubular reabsorption of bicarbonate in normocalcaemic rats with chronic hyperparathyroidism
JAEGER P, JONES W, KASHGARIAN M, SEGRE G, HAYSLETT J. Parathyroid hormone directly inhibits tubular reabsorption of bicarbonate in normocalcaemic rats with chronic hyperparathyroidism. European Journal Of Clinical Investigation 1987, 17: 415-420. PMID: 3121345, DOI: 10.1111/j.1365-2362.1987.tb01136.x.Peer-Reviewed Original ResearchConceptsParathyroid hormonePTH infusionChronic hyperparathyroidismPlasma calciumAnimal modelsEffect of PTHProximal HCO3 reabsorptionChronic metabolic acidosisGroups of animalsPrimary hyperparathyroidismAlzet minipumpsSerum calciumTubular reabsorptionAcute studyMetabolic acidosisMetabolic alkalosisRenal handlingTubular acidificationAcid secretionGroup IIHCO3- reabsorptionFree dietHyperparathyroidismCa-free dietNormal levels
1979
A micropuncture study of the renal handling of lithium
Hayslett J, Kashgarian M. A micropuncture study of the renal handling of lithium. Pflügers Archiv - European Journal Of Physiology 1979, 380: 159-163. PMID: 573443, DOI: 10.1007/bf00582152.Peer-Reviewed Original ResearchConceptsMicropuncture studiesProximal tubulesLoop of HenleTubular fluid samplesNephron sitesNet transepithelial movementRenal handlingLithium reabsorptionDistal tubulesClearance studiesTubular fluidProximal convolutionExperimental animalsDistal portionFluid samplesTubulesTransepithelial movementHenleNephron
1969
Physiologic studies in renal osteodystrophy treated by subtotal parathyroidectomy
Gill G, Pallotta J, Kashgarian M, Kessner D, Epstein F. Physiologic studies in renal osteodystrophy treated by subtotal parathyroidectomy. The American Journal Of Medicine 1969, 46: 930-940. PMID: 5797916, DOI: 10.1016/0002-9343(69)90095-3.Peer-Reviewed Original ResearchConceptsSubtotal parathyroidectomyParathyroid hormoneRenal osteodystrophyAbnormal renal handlingAdvanced renal insufficiencyOsteitis fibrosa cysticaRenal tubular reabsorptionRoentgenologic evidenceRenal insufficiencyFibrosa cysticaPreoperative levelsMetastatic calcificationUremic patientsTubular reabsorptionParathyroid tissueMedullary cystsRenal handlingPhysiologic studiesPatientsParathyroidectomyBone healingHormoneOsteodystrophyHypercalciuriaCystica