1998
Heat-shock protein 25 induction and redistribution during actin reorganization after renal ischemia
Aufricht C, Ardito T, Thulin G, Kashgarian M, Siegel N, Van Why S. Heat-shock protein 25 induction and redistribution during actin reorganization after renal ischemia. American Journal Of Physiology 1998, 274: f215-f222. PMID: 9458842, DOI: 10.1152/ajprenal.1998.274.1.f215.Peer-Reviewed Original ResearchConceptsHSP-25Renal ischemiaHeat shock protein 25Ischemic renal injuryH reflowRat renal cortexControl proximal tubulesRenal injuryPostischemic recoveryRenal cortexIschemiaProximal tubulesIntracytoplasmic accumulationPeak levelsHeat shock proteinsProtein 25Actin stainingInsoluble cytoskeletal fractionPunctate accumulationsCytoskeletal disruptionSmall heat shock proteinsRegulatory roleInductionIntracellular distributionCytoskeletal fraction
1988
Metabolic and functional consequences of inhibiting adenosine deaminase during renal ischemia in rats.
Stromski M, van Waarde A, Avison M, Thulin G, Gaudio K, Kashgarian M, Shulman R, Siegel N. Metabolic and functional consequences of inhibiting adenosine deaminase during renal ischemia in rats. Journal Of Clinical Investigation 1988, 82: 1694-1699. PMID: 3263396, PMCID: PMC442739, DOI: 10.1172/jci113782.Peer-Reviewed Original ResearchConceptsPostischemic restorationFunctional recoveryBilateral renal artery occlusionAdenosine deaminaseResidual nucleotide poolRenal artery occlusionEnd of ischemiaMin of ischemiaMin of reflowArtery occlusionAdenine nucleotide poolPostischemic recoveryRenal ischemiaNucleotide poolIschemia resultsUntreated animalsDegradation of ATPIschemiaBasal levelsRenal ATPATP levelsInitial recoveryRatsInsultFunctional consequences