2020
Urine interleukin-9 and tumor necrosis factor-α for prognosis of human acute interstitial nephritis
Moledina DG, Wilson FP, Kukova L, Obeid W, Luciano R, Kuperman M, Moeckel GW, Kashgarian M, Perazella MA, Cantley LG, Parikh CR. Urine interleukin-9 and tumor necrosis factor-α for prognosis of human acute interstitial nephritis. Nephrology Dialysis Transplantation 2020, 36: 1851-1858. PMID: 33125471, PMCID: PMC8476079, DOI: 10.1093/ndt/gfaa169.Peer-Reviewed Original ResearchConceptsAcute interstitial nephritisTumor necrosis factorCorticosteroid useIL-9Interstitial nephritisNecrosis factorAcute kidney injuryIL-9 levelsGlomerular filtration rateSubset of patientsCohort of participantsImmunosuppressive therapyTubulointerstitial infiltratesKidney injuryMedian eGFRKidney functionUrine biomarkersInterstitial fibrosisFiltration rateHistological featuresClinical trialsInterleukin-9PatientsEGFRComplete data
1989
Protection of the kidney against ischemic injury by inhibition of 5'-nucleotidase
Van Waarde A, Stromski M, Thulin G, Gaudio K, Kashgarian M, Shulman R, Siegel N. Protection of the kidney against ischemic injury by inhibition of 5'-nucleotidase. American Journal Of Physiology 1989, 256: f298-f305. PMID: 2537026, DOI: 10.1152/ajprenal.1989.256.2.f298.Peer-Reviewed Original ResearchConceptsRenal ischemic insultResidual nucleotide poolMin of ischemiaRenal ATP contentFunctional recoveryIschemic injuryIschemic insultKidney functionRenal ischemiaIntramuscular injectionUntreated ratsRapid initial recoveryATP restorationRat kidneyRenal ATPIschemiaInitial recoveryKidneyRatsATP contentInsultFunctional consequencesNucleotide poolMagnetic resonanceAMPCP
1988
Beneficial effect of thyroxin in the treatment of ischemic acute renal failure
Sutter P, Thulin G, Stromski M, Ardito T, Gaudio K, Kashgarian M, Siegel N. Beneficial effect of thyroxin in the treatment of ischemic acute renal failure. Pediatric Nephrology 1988, 2: 1-7. PMID: 2856365, DOI: 10.1007/bf00870370.Peer-Reviewed Original ResearchConceptsAcute renal failureIschemic acute renal failureRenal failureIschemic controlsNormal salineSaline-treated ischemic controlsBeneficial effectsBetter kidney functionDose of T4Min of reflowT4-treated ratsEffect of thyroxinRenal functionKidney functionNS animalsRenal ischemiaInulin clearanceSaline controlsDay 3Day 7IschemiaT4 animalsRenal ATPCellular mechanismsSignificant increase