1984
Beneficial effect of thyroxin on recovery from toxic acute renal failure
Siegel N, Gaudio K, Katz L, Reilly H, Ardito T, Hendler F, Kashgarian M. Beneficial effect of thyroxin on recovery from toxic acute renal failure. Kidney International 1984, 25: 906-911. PMID: 6471672, DOI: 10.1038/ki.1984.108.Peer-Reviewed Original ResearchConceptsToxic acute renal failureAcute renal failureNormal salineRenal failureBeneficial effectsInjected ratsOnly normal salineT4-treated ratsEffect of thyroxinNonspecific systemic effectsT4-treated animalsRenal insultHemodynamic effectsRenal functionRenal injuryControl ratsGlomerular functionUrine flowSimilar doseSystemic effectsEnhanced recoveryPrompt recoveryKidney preparationRatsFENa
1982
Accelerated recovery of single nephron function by the postischemic infusion of ATP-MgCl2
Gaudio K, Taylor M, Chaudry I, Kashgarian M, Siegel N. Accelerated recovery of single nephron function by the postischemic infusion of ATP-MgCl2. Kidney International 1982, 22: 13-20. PMID: 7120752, DOI: 10.1038/ki.1982.126.Peer-Reviewed Original ResearchConceptsClearance of inulinSingle nephron functionATP-MgCl2Proximal tubular pressureNephron functionTubular pressureBeneficial effectsRenal artery ischemiaSaline-treated animalsSaline-treated ratsCourse of recoveryGroups of animalsPostischemic administrationArtery ischemiaPattern of recoveryCIN 1Postischemic infusionInitial insultInulin clearanceInitial improvementControl animalsMost epithelial cellsEnhanced recoveryWhole kidneyTubular fluid
1980
ISCHEMIC ACUTE RENAL FAILURE: ENHANCED RECOVERY OF SUPERFICIAL NEPHRON FUNCTION BY ATP-MGCL2
Gaudio K, Sieqel N, Chaudry I, Kashgarian M. ISCHEMIC ACUTE RENAL FAILURE: ENHANCED RECOVERY OF SUPERFICIAL NEPHRON FUNCTION BY ATP-MGCL2. Pediatric Research 1980, 14: 1017-1017. DOI: 10.1203/00006450-198008000-00261.Peer-Reviewed Original ResearchSuperficial single nephron GFRWhole kidney GFRIntratubular obstructionATP-MgCl2Superficial nephronsHemodynamic factorsBilateral renal artery occlusionCortical blood flow distributionTotal renal blood flowControl valuesIschemic renal insultRenal artery occlusionRenal blood flowSingle nephron GFRBlood flow distributionProximal tubular pressureRenal insultArtery occlusionNephron GFREnhancement of recoveryKidney GFRBlood flowEnhanced recoveryNormal valuesGFR