2020
Goal-Directed Fluid Therapy and Postoperative Outcomes in an Enhanced Recovery Program for Colorectal Surgery: A Propensity Score-Matched Multicenter Study
Zorrilla-Vaca A, Mena G, Ripolles-Melchor J, Abad-Motos A, Aldecoa C, Lorente J, Ramirez-Rodriguez J, Grant M. Goal-Directed Fluid Therapy and Postoperative Outcomes in an Enhanced Recovery Program for Colorectal Surgery: A Propensity Score-Matched Multicenter Study. The American Surgeon 2020, 87: 1189-1195. PMID: 33342254, DOI: 10.1177/0003134820973365.Peer-Reviewed Original ResearchConceptsGoal-directed fluid therapyEnhanced recovery programmeAcute kidney injurySurgical site infectionColorectal surgeryPostoperative outcomesFluid therapyPostoperative acute kidney injuryPropensity score-matched analysisComparable baseline demographicsMajor postoperative outcomesAdequate tissue perfusionRates of morbidityHospital stayKidney injuryBaseline demographicsCohort studyConventional careERAS programAnastomotic dehiscenceMajor surgerySite infectionPulmonary edemaMulticenter studyTherapy patients
2019
Evidence Review Conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery
Ban K, Gibbons M, Ko C, Wick E, Cannesson M, Scott M, Grant M, Wu C. Evidence Review Conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery. Anesthesia & Analgesia 2019, Publish Ahead of Print: &na;. PMID: 29649026, DOI: 10.1213/ane.0000000000003366.Peer-Reviewed Original ResearchMeSH KeywordsAnesthesiaAnesthesiologyAnti-Bacterial AgentsAntibiotic ProphylaxisCarbohydratesColorectal NeoplasmsColorectal SurgeryEvidence-Based MedicineFluid TherapyHumansPatient SafetyPerioperative CarePiperidinesQuality of Health CareRandomized Controlled Trials as TopicSafety ManagementSurgical Procedures, OperativeThromboembolismTreatment OutcomeUnited StatesUnited States Agency for Healthcare Research and QualityUrinary Tract InfectionsConceptsSurgical careJohns Hopkins Medicine Armstrong InstituteCatheter-associated urinary tract infectionsGoal-directed fluid therapyHealthcare ResearchMultimodal analgesic regimensVenous thromboembolic eventsSurgical site infectionUrinary tract infectionQuality Safety ProgramProfessional associations/societiesGuidelines/recommendationsAssociation/SocietyAnalgesic regimensAntibiotic prophylaxisEvidence-based processThromboembolic eventsTract infectionsBlood transfusionCarbohydrate loadingPerioperative careSite infectionPostoperative phaseFluid therapySurgical outcomesEnhanced Recovery after Surgery for Colorectal Surgery: A Review of the Economic Implications
Stone A, Grant M, Wu C, Wick E. Enhanced Recovery after Surgery for Colorectal Surgery: A Review of the Economic Implications. Clinics In Colon And Rectal Surgery 2019, 32: 129-133. PMID: 30833862, PMCID: PMC6395088, DOI: 10.1055/s-0038-1676478.Peer-Reviewed Original ResearchHospital-acquired infectionsColorectal surgeryERAS programEnhanced recoverySuccessful ERAS programsSurgical site infectionQuality Improvement ProgramPerioperative protocolSite infectionSurgery programSurgeryFrontline providersPotential cost savingsHospitalInfectionHospital executivesStayCost savingsImprovement programsOverall lengthERAS
2017
Dedicated Operating Room Teams and Clinical Outcomes in an Enhanced Recovery after Surgery Pathway for Colorectal Surgery
Grant MC, Hanna A, Benson A, Hobson D, Wu CL, Yuan CT, Rosen M, Wick EC. Dedicated Operating Room Teams and Clinical Outcomes in an Enhanced Recovery after Surgery Pathway for Colorectal Surgery. Journal Of The American College Of Surgeons 2017, 226: 267-276. PMID: 29274837, DOI: 10.1016/j.jamcollsurg.2017.12.010.Peer-Reviewed Original ResearchConceptsClinical outcomesProcess measure complianceEnhanced recoveryMeasure complianceOperating room teamSurgery programAnesthesia providersSurgical site infectionLength of stayHigh complianceColorectal surgeryERAS implementationERAS programSite infectionPerioperative careSurgery pathwayProvider teamProtocol elementsNurse anesthetistsIndividual providersDedicated teamOutcomesSignificant increaseSignificant reductionAnesthesiologistsIs enhanced recovery enough for reducing 30-d readmissions after surgery?
Fabrizio A, Grant M, Siddiqui Z, Alimi Y, Gearhart S, Wu C, Efron J, Wick E. Is enhanced recovery enough for reducing 30-d readmissions after surgery? Journal Of Surgical Research 2017, 217: 45-53. PMID: 28602223, DOI: 10.1016/j.jss.2017.04.007.Peer-Reviewed Original ResearchConceptsEnhanced recovery pathwaySurgical site infectionSite infectionSingle tertiary care centerPostoperative surgical site infectionIndex hospitalization lengthTertiary care centerEnhanced recovery programmeLength of stayTransitions of carePatient care experiencesColorectal surgeryReadmission ratesReduced readmissionsHospitalization lengthRetrospective studyCare transitionsCare centerPatient outcomesReadmissionSymptom monitoringSimilar cohortEnhanced recoveryHome transfersCare experiencesImpact of Enhanced Recovery After Surgery and Fast Track Surgery Pathways on Healthcare-associated Infections
Grant M, Yang D, Wu C, Makary M, Wick E. Impact of Enhanced Recovery After Surgery and Fast Track Surgery Pathways on Healthcare-associated Infections. Annals Of Surgery 2017, 265: 68-79. PMID: 28009729, DOI: 10.1097/sla.0000000000001703.Peer-Reviewed Original ResearchConceptsHealthcare-associated infectionsSurgical site infectionUrinary tract infectionLung infectionFTS protocolFast-track surgery pathwaysFast-track surgery protocolMajor healthcare-associated infectionPostoperative lung infectionLength of staySignificant reductionPostoperative incidenceHospital lengthColorectal surgerySurgery protocolTract infectionsPerioperative carePrimary outcomeSite infectionRandomized trialsSurgery pathwayPelvic surgerySubgroup analysisSurgical careHigh risk
2016
The Impact of Neuraxial Versus General Anesthesia on the Incidence of Postoperative Surgical Site Infections Following Knee or Hip Arthroplasty
Zorrilla-Vaca A, Grant MC, Mathur V, Li J, Wu CL. The Impact of Neuraxial Versus General Anesthesia on the Incidence of Postoperative Surgical Site Infections Following Knee or Hip Arthroplasty. Regional Anesthesia & Pain Medicine 2016, 41: 555-563. PMID: 27380106, DOI: 10.1097/aap.0000000000000437.Peer-Reviewed Original ResearchConceptsPostoperative surgical site infectionSurgical site infectionKnee arthroplastyHip arthroplastySite infectionNeuraxial anesthesiaGeneral anesthesiaSubgroup analysisOdds ratioDevelopment of SSIPooled unadjusted odds ratioUnadjusted odds ratioLarge observational trialsRandom-effects modelOverall beneficial effectObservational trialAnesthetic techniqueAnesthesia techniquesJoint arthroplastyInclusion criteriaTrial designArthroplastyMeta-AnalysisAnesthesiaPotential association