2023
Ultrafiltration in cardiac surgery: Results of a systematic review and meta-analysis
Hensley N, Colao J, Zorrilla-Vaca A, Nanavati J, Lawton J, Raphael J, Mazzeffi M, Wierschke C, Kostibas M, Cho B, Frank S, Grant M. Ultrafiltration in cardiac surgery: Results of a systematic review and meta-analysis. Perfusion 2023, 39: 743-751. PMID: 36795704, DOI: 10.1177/02676591231157970.Peer-Reviewed Original ResearchIntraoperative red cell transfusionsRed cell transfusionAcute kidney injuryCell transfusionObservational studySystematic reviewConventional ultrafiltrationIntraoperative blood transfusionEffect of hemodilutionMeta-Analyses (PRISMA) statementPreferred Reporting ItemsRed cell unitsWeb of ScienceKidney injuryBlood transfusionCardiac surgeryModified ultrafiltrationPrimary outcomeCardiopulmonary bypassCochrane LibraryTransfusionElectrolyte balanceReporting ItemsCell unitsReview
2020
Enhanced Recovery Programs for Colorectal Surgery and Postoperative Acute Kidney Injury: Results From a Systematic Review and Meta-Analysis of Observational Studies
Zorrilla-Vaca A, Mena G, Cata J, Healy R, Grant M. Enhanced Recovery Programs for Colorectal Surgery and Postoperative Acute Kidney Injury: Results From a Systematic Review and Meta-Analysis of Observational Studies. The American Surgeon 2020, 87: 1444-1451. PMID: 33375852, DOI: 10.1177/0003134820954846.Peer-Reviewed Original ResearchConceptsPostoperative acute kidney injuryAcute kidney injuryObservational studyKidney injuryColorectal surgeryConventional careSystematic reviewHigh-risk patient populationConventional perioperative carePerioperative health careRestrictive fluid administrationEnhanced recovery programmeRisk patient populationEvidence-based measuresHemodynamic goalsPostoperative recoveryERP patientsPerioperative careFluid administrationNephrotoxic agentsPatient populationPooled resultsGreater oddsRecovery programMeta-AnalysisRetrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis.
Hensley N, Gyi R, Zorrilla-Vaca A, Choi C, Lawton J, Brown C, Frank S, Grant M, Cho B. Retrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis. Anesthesia & Analgesia 2020, 132: 100-107. PMID: 32947294, DOI: 10.1213/ane.0000000000005151.Peer-Reviewed Original ResearchConceptsAllogeneic red cell transfusionRed cell transfusionAcute kidney injuryCardiac surgical patientsCell transfusionCardiopulmonary bypassObservational studySystematic reviewAutologous primingRAP patientsSurgical patientsCardiac surgeryAdditional high-quality prospective studiesPerioperative allogeneic red cell transfusionIntraoperative red cell transfusionsHigh-quality prospective studiesSignificant increased oddsAllogeneic transfusionKidney injuryAdverse eventsControl patientsSecondary outcomesStroke outcomeOrgan injuryPrimary outcome
2019
On‐label compared to off‐label four‐factor prothrombin complex concentrate use: a retrospective, observational study
Cho B, Jung Y, DeMario V, Lau E, Podlasek S, Grant M, Gehrie E, Frank S. On‐label compared to off‐label four‐factor prothrombin complex concentrate use: a retrospective, observational study. Transfusion 2019, 59: 2678-2684. PMID: 31121073, DOI: 10.1111/trf.15355.Peer-Reviewed Original ResearchConceptsUrgent reversalLabel useMortality rateFour-factor prothrombin complex concentrateAcute major bleedingVitamin K antagonistsProthrombin complex concentrate useProthrombin complex concentrateOff-label useCoagulation factor deficienciesHospital mortalityMajor bleedingK antagonistsPatient characteristicsClinical outcomesBlood utilizationExpensive treatment optionsLabel indicationsSingle institutionTreatment optionsComplex concentrateObservational studyFactor deficiencyInvasive proceduresOff label
2018
Intraoperative cerebral oximetry-based management for optimizing perioperative outcomes: a meta-analysis of randomized controlled trials
Zorrilla-Vaca A, Healy R, Grant M, Joshi B, Rivera-Lara L, Brown C, Mirski M. Intraoperative cerebral oximetry-based management for optimizing perioperative outcomes: a meta-analysis of randomized controlled trials. Journal Canadien D'anesthésie 2018, 65: 529-542. PMID: 29427259, DOI: 10.1007/s12630-018-1065-7.Peer-Reviewed Original ResearchConceptsPostoperative cognitive dysfunctionIntensive care unitIntraoperative cerebral oximetryCerebral oximetryPostoperative deliriumIncidence of POCDProspective clinical trialsOverall hospital LOSPredictors of outcomeGoogle Scholar databasesHospital LOSPurposeAlthough evidenceHospital lengthPerioperative outcomesPostoperative outcomesSecondary outcomesPrimary outcomeCare unitClinical outcomesIntraoperative managementLarge RCTsCochrane LibraryClinical trialsCognitive dysfunctionObservational study
2017
Epidemiology of septic meningitis associated with neuraxial anesthesia: a historical review and meta-analysis.
Zorrilla-Vaca A, Healy R, Rivera-Lara L, Grant M, Maragakis L, Escandón-Vargas K, Mirski M. Epidemiology of septic meningitis associated with neuraxial anesthesia: a historical review and meta-analysis. Minerva Anestesiologica 2017, 84: 363-377. PMID: 29108403, DOI: 10.23736/s0375-9393.17.11920-6.Peer-Reviewed Original ResearchConceptsSeptic meningitisNeuraxial anesthesiaEpidural anesthesiaOverall mortality rateCommon risk factorsCase report articlesSpinal anesthesiaSymptom onsetEpidural anestheticsTrue incidenceRisk factorsRegional anesthesiaObservational studyLocal anestheticsMeningitisEpidemiological studiesMortality rateAnesthesiaSystematic reviewSurgical masksCommon bacteriaFrequent formEpiduralStaphylococcus aureusAnestheticsRelation between bispectral index measurements of anesthetic depth and postoperative mortality: a meta-analysis of observational studies
Zorrilla-Vaca A, Healy R, Wu C, Grant M. Relation between bispectral index measurements of anesthetic depth and postoperative mortality: a meta-analysis of observational studies. Journal Canadien D'anesthésie 2017, 64: 597-607. PMID: 28361391, DOI: 10.1007/s12630-017-0872-6.Peer-Reviewed Original ResearchConceptsDepth of anesthesiaLow bispectral indexObservational studyBispectral indexSubgroup analysisSignificant associationResultsEight observational studiesLong-term mortalityPooled effect sizeMain electronic databasesBispectral index measurementsRandom-effects modelPostoperative mortalityHazard ratioIntroductionThe associationRandomized trialsInclusion criteriaAnesthesiaElectronic databasesNarrative reviewPotential associationAnesthetic depthMethodsThe literatureMortalityAnesthesia depth