2024
Practice Advisory on the Implementation of Preoperative Anemia Management: The Society of Cardiovascular Anesthesiologists and the Society for the Advancement of Patient Blood Management
Klompas A, Hensley N, Burt J, Grant M, Guinn N, Patel P, Popescu W, Raphael J, Salenger R, Shore-Lesserson L, Warner M. Practice Advisory on the Implementation of Preoperative Anemia Management: The Society of Cardiovascular Anesthesiologists and the Society for the Advancement of Patient Blood Management. Anesthesia & Analgesia 2024 DOI: 10.1213/ane.0000000000007321.Peer-Reviewed Original ResearchPatient blood managementAdvancement of Patient Blood ManagementBlood managementPreoperative anemiaCardiac surgeryAnemia managementRed blood cell transfusionAssociated with worse outcomesPreoperative anemia clinicPatient blood management programBlood cell transfusionAcute kidney injuryBlood management programPreoperative anemia managementImproving clinical outcomesSociety of Cardiovascular Anesthesiologists (SCASociety of Cardiovascular AnesthesiologistsAnemia programCell transfusionAnemia clinicEducation of patientsAllogeneic transfusionCardiovascular complicationsKidney injuryTreatment algorithm
2023
Ultrafiltration in cardiac surgery: Results of a systematic review and meta-analysis
Hensley N, Colao J, Zorrilla-Vaca A, Nanavati J, Lawton J, Raphael J, Mazzeffi M, Wierschke C, Kostibas M, Cho B, Frank S, Grant M. Ultrafiltration in cardiac surgery: Results of a systematic review and meta-analysis. Perfusion 2023, 39: 743-751. PMID: 36795704, DOI: 10.1177/02676591231157970.Peer-Reviewed Original ResearchIntraoperative red cell transfusionsRed cell transfusionAcute kidney injuryCell transfusionObservational studySystematic reviewConventional ultrafiltrationIntraoperative blood transfusionEffect of hemodilutionMeta-Analyses (PRISMA) statementPreferred Reporting ItemsRed cell unitsWeb of ScienceKidney injuryBlood transfusionCardiac surgeryModified ultrafiltrationPrimary outcomeCardiopulmonary bypassCochrane LibraryTransfusionElectrolyte balanceReporting ItemsCell unitsReview
2022
Controversies in enhanced recovery after cardiac surgery
Shaw A, Guinn N, Brown J, Arora R, Lobdell K, Grant M, Gan T, Engelman D. Controversies in enhanced recovery after cardiac surgery. Perioperative Medicine 2022, 11: 19. PMID: 35477446, PMCID: PMC9047268, DOI: 10.1186/s13741-022-00250-7.Peer-Reviewed Original ResearchCardiac surgeryEnhanced recoveryStandardized perioperative careAcute kidney injuryGoal-directed therapyPatient blood managementEvidence-based best practicesSignificant evidence gapsAnalgesic reductionKidney injuryOverall morbidityPerioperative carePatient-centric carePreventable morbidityMyocardial protectionBlood managementOperative techniqueEvidence gapsPerioperative medicineSurgeryOperating roomQuality InitiativeMorbidityMortalitySignificant controversy
2020
Enhanced Recovery Programs for Colorectal Surgery and Postoperative Acute Kidney Injury: Results From a Systematic Review and Meta-Analysis of Observational Studies
Zorrilla-Vaca A, Mena G, Cata J, Healy R, Grant M. Enhanced Recovery Programs for Colorectal Surgery and Postoperative Acute Kidney Injury: Results From a Systematic Review and Meta-Analysis of Observational Studies. The American Surgeon 2020, 87: 1444-1451. PMID: 33375852, DOI: 10.1177/0003134820954846.Peer-Reviewed Original ResearchConceptsPostoperative acute kidney injuryAcute kidney injuryObservational studyKidney injuryColorectal surgeryConventional careSystematic reviewHigh-risk patient populationConventional perioperative carePerioperative health careRestrictive fluid administrationEnhanced recovery programmeRisk patient populationEvidence-based measuresHemodynamic goalsPostoperative recoveryERP patientsPerioperative careFluid administrationNephrotoxic agentsPatient populationPooled resultsGreater oddsRecovery programMeta-AnalysisGoal-Directed Fluid Therapy and Postoperative Outcomes in an Enhanced Recovery Program for Colorectal Surgery: A Propensity Score-Matched Multicenter Study
Zorrilla-Vaca A, Mena G, Ripolles-Melchor J, Abad-Motos A, Aldecoa C, Lorente J, Ramirez-Rodriguez J, Grant M. Goal-Directed Fluid Therapy and Postoperative Outcomes in an Enhanced Recovery Program for Colorectal Surgery: A Propensity Score-Matched Multicenter Study. The American Surgeon 2020, 87: 1189-1195. PMID: 33342254, DOI: 10.1177/0003134820973365.Peer-Reviewed Original ResearchConceptsGoal-directed fluid therapyEnhanced recovery programmeAcute kidney injurySurgical site infectionColorectal surgeryPostoperative outcomesFluid therapyPostoperative acute kidney injuryPropensity score-matched analysisComparable baseline demographicsMajor postoperative outcomesAdequate tissue perfusionRates of morbidityHospital stayKidney injuryBaseline demographicsCohort studyConventional careERAS programAnastomotic dehiscenceMajor surgerySite infectionPulmonary edemaMulticenter studyTherapy patientsRetrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis.
Hensley N, Gyi R, Zorrilla-Vaca A, Choi C, Lawton J, Brown C, Frank S, Grant M, Cho B. Retrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis. Anesthesia & Analgesia 2020, 132: 100-107. PMID: 32947294, DOI: 10.1213/ane.0000000000005151.Peer-Reviewed Original ResearchConceptsAllogeneic red cell transfusionRed cell transfusionAcute kidney injuryCardiac surgical patientsCell transfusionCardiopulmonary bypassObservational studySystematic reviewAutologous primingRAP patientsSurgical patientsCardiac surgeryAdditional high-quality prospective studiesPerioperative allogeneic red cell transfusionIntraoperative red cell transfusionsHigh-quality prospective studiesSignificant increased oddsAllogeneic transfusionKidney injuryAdverse eventsControl patientsSecondary outcomesStroke outcomeOrgan injuryPrimary outcomeRisk factors for acute kidney injury in an enhanced recovery pathway for colorectal surgery
Zorrilla-Vaca A, Mena G, Ripolles-Melchor J, Lorente J, Ramirez-Rodriguez J, Grant M. Risk factors for acute kidney injury in an enhanced recovery pathway for colorectal surgery. Surgery Today 2020, 51: 537-544. PMID: 32785846, DOI: 10.1007/s00595-020-02107-2.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAge FactorsAgedAged, 80 and overColonCreatinineDigestive System Surgical ProceduresEnhanced Recovery After SurgeryFemaleHumansMaleMalnutritionMiddle AgedMulticenter Studies as TopicNutritional StatusPostoperative ComplicationsProspective StudiesRectumRisk FactorsROC CurveSerum AlbuminConceptsPostoperative acute kidney injuryAcute kidney injuryColorectal surgeryRisk factorsKidney injuryLow preoperative albumin levelRecovery pathwaysPerioperative patient outcomesPreoperative albumin levelEnhanced recovery pathwayIndependent risk factorProspective cohort studyPoor clinical outcomeDirect healthcare costsOpen surgical approachMalnourished patientsCohort studyAlbumin levelsASA IIILarge multicenterPreoperative interventionClinical outcomesMultivariable analysisOverall incidenceModifiable factors
2008
Is Aprotinin Safe to Use in a Cohort at Increased Risk for Thrombotic Events: Results From a Randomized, Prospective Trial in Off-Pump Coronary Artery Bypass
Grant M, Kon Z, Joshi A, Christenson E, Kallam S, Burris N, Gu J, Poston R. Is Aprotinin Safe to Use in a Cohort at Increased Risk for Thrombotic Events: Results From a Randomized, Prospective Trial in Off-Pump Coronary Artery Bypass. The Annals Of Thoracic Surgery 2008, 86: 815-822. PMID: 18721566, PMCID: PMC2649734, DOI: 10.1016/j.athoracsur.2008.04.047.Peer-Reviewed Original ResearchConceptsAcute kidney injuryCoronary artery bypassThrombotic eventsAprotinin levelsAprotinin useArtery bypassDay 3Off-pump coronary artery bypassMore acute kidney injuryPostoperative acute kidney injurySubsequent acute kidney injuryPump coronary artery bypassAcute graft failureAdverse thrombotic eventsWeight-based protocolPercentage of patientsGlomerular filtration rateFavorable safety profileMultiple randomized trialsPostoperative hypercoagulable stateEGFR declineCerebrovascular eventsKidney injuryLower eGFRPlacebo group