Dexmedetomidine improves pulmonary outcomes in thoracic surgery under one-lung ventilation: A meta-analysis
Zorrilla-Vaca A, Grant M, Law M, Messinger C, Pelosi P, Varelmann D. Dexmedetomidine improves pulmonary outcomes in thoracic surgery under one-lung ventilation: A meta-analysis. Journal Of Clinical Anesthesia 2023, 93: 111345. PMID: 37988813, PMCID: PMC11034816, DOI: 10.1016/j.jclinane.2023.111345.Peer-Reviewed Original ResearchAcute respiratory distress syndromePostoperative pulmonary complicationsOne-lung ventilationThoracic surgeryDexmedetomidine groupPlacebo groupPostoperative atelectasisRandomized trialsOdds ratioIncidence of PPCsImpact of dexmedetomidineIntraoperative respiratory mechanicsPostoperative lung functionRespiratory distress syndromeML/cmHRandom-effects modelPostoperative pneumoniaPulmonary complicationsPulmonary outcomesIntrapulmonary shuntPostoperative FEV1Secondary outcomesDistress syndromeLung functionPrimary outcome