2017
Preserved Analgesia With Reduction in Opioids Through the Use of an Acute Pain Protocol in Enhanced Recovery After Surgery for Open Hepatectomy
Grant M, Sommer P, He C, Li S, Page A, Stone A, Hobson D, Wick E, Wu C. Preserved Analgesia With Reduction in Opioids Through the Use of an Acute Pain Protocol in Enhanced Recovery After Surgery for Open Hepatectomy. Regional Anesthesia & Pain Medicine 2017, 42: 451-457. PMID: 28525409, DOI: 10.1097/aap.0000000000000615.Peer-Reviewed Original ResearchConceptsOpen hepatectomyPain scoresERAS pathwayERAS protocolEnd pointPain controlSelf-reported pain scoresAcute pain protocolsAverage pain scoreLess morphine equivalentsMorphine equivalent requirementsOpioid-based medicationsProvision of fluidsLiver resection surgeryOptimal pain controlUse of epiduralsLength of stayHigh-risk procedurePostoperative end pointsERAS settingMorphine equivalentsNonepidural groupOpioid requirementsPerioperative opioidsEpidural analgesia
2016
The Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting
Grant M, Lee H, Page A, Hobson D, Wick E, Wu C. The Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2016, 122: 976-985. PMID: 26991615, DOI: 10.1213/ane.0000000000001120.Peer-Reviewed Original ResearchConceptsPreoperative gabapentinPrimary end pointEnd pointPostoperative nauseaSide effectsPrevention of PONVHigh-risk surgerySignificant reductionGabapentin administrationPostoperative sedationThiopental inductionOpioid analgesiaPostoperative painAntiemetic effectRepeat dosingGeneral anesthesiaSubgroup analysisPONVPooled effectNauseaVomitingGabapentinPrimary analysisSecondary analysisTrialsThe Effect of Intravenous Midazolam on Postoperative Nausea and Vomiting
Grant M, Kim J, Page A, Hobson D, Wick E, Wu C. The Effect of Intravenous Midazolam on Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2016, 122: 656-663. PMID: 26332858, DOI: 10.1213/ane.0000000000000941.Peer-Reviewed Original ResearchConceptsPostoperative nauseaHigh-risk surgical patientsRescue antiemetic useUse of thiopentalHours of surgeryHigh-risk surgeryTrials of adultsMultimodal therapeutic approachIndividual subgroup analysisAntiemetic administrationAntiemetic useOverall PONVIntravenous midazolamSurgical patientsGeneral anesthesiaFemale sexSubgroup analysisPONVSurgical proceduresTherapeutic approachesNauseaVomitingMidazolamEnd pointTrials