2022
Early Return to Intended Oncologic Therapy after implementation of an Enhanced Recovery After Surgery pathway for gastric cancer surgery
Garcia-Nebreda M, Zorrilla-Vaca A, Ripollés-Melchor J, Abad-Motos A, Alvaro Cifuentes E, Abad-Gurumeta A, Mena G, Grant M, Paseiro-Crespo G. Early Return to Intended Oncologic Therapy after implementation of an Enhanced Recovery After Surgery pathway for gastric cancer surgery. Langenbeck's Archives Of Surgery 2022, 407: 2293-2300. PMID: 35441358, DOI: 10.1007/s00423-022-02515-7.Peer-Reviewed Original ResearchConceptsGastric cancer surgeryCancer surgeryERAS pathwayAdjuvant therapySurgery pathwayOncologic therapyGastric adenocarcinomaEnhanced recoveryPostoperative oncologic outcomesPre-ERAS periodERAS groupHospital stayOncologic outcomesPrimary outcomeShorter LOSResultsSeventy patientsEarly returnSurgeryIntervention studiesTherapyPatientsMedian differenceAdenocarcinomaOutcomesPathway
2017
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review
Wick E, Grant M, Wu C. Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review. JAMA Surgery 2017, 152: 691-697. PMID: 28564673, DOI: 10.1001/jamasurg.2017.0898.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory agentsAnti-inflammatory agentsERAS pathwayPostoperative bleedingN-methyl-D-aspartate (NMDA) classMultimodal analgesia approachGlutamate receptor antagonistsCurrent opioid epidemicComplex surgical proceduresAnalgesic regimensOpioid consumptionLess opioidsMultimodal analgesiaNarcotic analgesiaNonopioid analgesicsHospital dischargeMost patientsPain managementRegional analgesiaSurgery pathwayReceptor antagonistClinical trialsOpioid epidemicEffective adjunctSurgical carePreserved Analgesia With Reduction in Opioids Through the Use of an Acute Pain Protocol in Enhanced Recovery After Surgery for Open Hepatectomy
Grant M, Sommer P, He C, Li S, Page A, Stone A, Hobson D, Wick E, Wu C. Preserved Analgesia With Reduction in Opioids Through the Use of an Acute Pain Protocol in Enhanced Recovery After Surgery for Open Hepatectomy. Regional Anesthesia & Pain Medicine 2017, 42: 451-457. PMID: 28525409, DOI: 10.1097/aap.0000000000000615.Peer-Reviewed Original ResearchConceptsOpen hepatectomyPain scoresERAS pathwayERAS protocolEnd pointPain controlSelf-reported pain scoresAcute pain protocolsAverage pain scoreLess morphine equivalentsMorphine equivalent requirementsOpioid-based medicationsProvision of fluidsLiver resection surgeryOptimal pain controlUse of epiduralsLength of stayHigh-risk procedurePostoperative end pointsERAS settingMorphine equivalentsNonepidural groupOpioid requirementsPerioperative opioidsEpidural analgesia
2016
Patient outcomes and provider perceptions following implementation of a standardized perioperative care pathway for open liver resection
Page A, Gani F, Crowley K, Lee K, Grant M, Zavadsky T, Hobson D, Wu C, Wick E, Pawlik T. Patient outcomes and provider perceptions following implementation of a standardized perioperative care pathway for open liver resection. British Journal Of Surgery 2016, 103: 564-571. PMID: 26859713, DOI: 10.1002/bjs.10087.Peer-Reviewed Original ResearchConceptsPost-ERAS groupPerioperative care pathwaysERAS pathwayOpen liver surgeryHospital stayPerioperative outcomesPostoperative complicationsOpioid useLiver surgeryCare pathwayProviders' perceptionsMean pain scoreOpen liver resectionShorter hospital stayImproved perioperative outcomesGroup of patientsCent of providersPerioperative pathwayPain scoresERAS programLiver resectionSurgery pathwayDisease characteristicsHepatic surgeryHospital costs